67 Result(s)
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Open AccessModel based on the automated AI-driven CT quantification is effective for the diagnosis of refractory Mycoplasma pneumoniae pneumonia
The prediction of refractory Mycoplasma pneumoniae pneumonia (RMPP) remains a clinically significant challenge. This study aimed to develop an early predictive model utilizing artificial intelligence (AI)-deri...
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Open AccessSite selection and prediction of urban emergency shelter based on VGAE-RF model
As urban development accelerates and natural disasters occur more frequently, the urgency of develo** effective emergency shelter planning strategies intensifies. The shelter location selection method under ...
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Transcranial volumetric imaging using a conformal ultrasound patch
Accurate and continuous monitoring of cerebral blood flow is valuable for clinical neurocritical care and fundamental neurovascular research. Transcranial Doppler (TCD) ultrasonography is a widely used non-inv...
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Open AccessWell-defined diatomic catalysis for photosynthesis of C2H4 from CO2
Owing to the specific electronic-redistribution and spatial proximity, diatomic catalysts (DACs) have been identified as principal interest for efficient photoconversion of CO2 into C2H4. However, the predominant...
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Open AccessGRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer
Growth factor receptor-bound protein 2 (GRB2) is a cytoplasmic adapter for tyrosine kinase signaling and a nuclear adapter for homology-directed-DNA repair. Here we find nuclear GRB2 protects DNA at stalled re...
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Open AccessKisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src
Osteoclasts are over-activated as we age, which results in bone loss. Src deficiency in mice leads to severe osteopetrosis due to a functional defect in osteoclasts, indicating that Src function is essential in o...
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Open AccessSuppressing electron-phonon coupling in organic photovoltaics for high-efficiency power conversion
The nonradiative energy loss (∆Enr) is a critical factor to limit the efficiency of organic solar cells. Generally, strong electron-phonon coupling induced by molecular motion generates fast nonradiative decay an...
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Open AccessHOXA13 promotes the proliferation, migration, and invasion of nasopharyngeal carcinoma HNE1 cells by upregulating the expression of Snail and MMP-2
Homeobox A13 (HOXA13) has been verified as an oncogen in some malignancies. However, its role in nasopharyngeal carcinoma (NPC) is still unclear. This study aims to explore the role of HOXA13 in NPC and its un...
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Open AccessPan-cancer analysis reveals the prognostic and immunotherapeutic value of cytoskeleton-associated protein 2-like
Cytoskeleton-associated protein 2-like (CKAP2L), a cell cycle-related protein, is correlated to tumor progression in some tumors. But there were no pan-cancer studies on CKAP2L, and its role in cancer immunoth...
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Open AccessThe RNA-binding protein hnRNP F is required for the germinal center B cell response
The T cell-dependent (TD) antibody response involves the generation of high affinity, immunoglobulin heavy chain class-switched antibodies that are generated through germinal center (GC) response. This process...
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Open AccessA wearable cardiac ultrasound imager
Continuous imaging of cardiac functions is highly desirable for the assessment of long-term cardiovascular health, detection of acute cardiac dysfunction and clinical management of critically ill or surgical p...
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Open AccessA photoacoustic patch for three-dimensional imaging of hemoglobin and core temperature
Electronic patches, based on various mechanisms, allow continuous and noninvasive monitoring of biomolecules on the skin surface. However, to date, such devices are unable to sense biomolecules in deep tissues...
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Open AccessPan-cancer analysis of the prognostic and immunological role of PAQR4
Progestin and adipoQ receptor family member 4 (PAQR4) is a protein-coding gene. Recent studies have shown that PAQR4 is related to the development of multiple cancers. However, there is no systematic pan-cance...
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Open AccessNon-Hookean large elastic deformation in bulk crystalline metals
Crystalline metals can have large theoretical elastic strain limits. However, a macroscopic block of conventional crystalline metals practically suffers a very limited elastic deformation of <0.5% with a linea...
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Open AccessSpatiotemporal changes of bacterial communities during a cyanobacterial bloom in a subtropical water source reservoir ecosystem in China
Cyanobacterial blooms, which not only threaten the health and stability of aquatic ecosystems but also influence the microbial community within, emerges as one of the most concerning problems in China. However...
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Perovskite superlattices with efficient carrier dynamics
Compared with their three-dimensional (3D) counterparts, low-dimensional metal halide perovskites (2D and quasi-2D; B2An−1MnX3n+1, such as B = R-NH3+, A = HC(NH2)2+, Cs+; M = Pb2+, Sn2+; X = Cl−, Br−, I−) with pe...
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Open AccessEffect of sarcopenia and poor balance on vertebral spinal osteoporotic fracture in female rheumatoid arthritis
This study investigated the effect of poor balance and sarcopenia on vertebral spinal osteoporotic fracture (VOPF) in female rheumatoid arthritic (RA) patients. A total of 195 female RA and 126 normal subjects...
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Open AccessMulticenter phase II trial of Camrelizumab combined with Apatinib and Eribulin in heavily pretreated patients with advanced triple-negative breast cancer
In the later-line setting or for patients with PD-L1-negative tumors, immunotherapy-based regimens remain ineffective against advanced triple-negative breast cancer (TNBC). In this multicentered phase II trial...
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Open AccessManipulation of current rectification in van der Waals ferroionic CuInP2S6
Develo** a single-phase self-rectifying memristor with the continuously tunable feature is structurally desirable and functionally adaptive to dynamic environmental stimuli variations, which is the pursuit o...
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Open AccessRecovery and utilization of phosphorus from fruit and vegetable wastewater
Excessive discharge of phosphorus into the water bodies is the key factor to cause eutrophication. The fruit and vegetable wastewater contains large amounts of phosphorus, and it may be directly discharged int...
