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Open AccessDuodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis
Hepatocellular carcinoma (HCC) is rapidly increasing in the U.S. and is a leading cause of mortality for patients with cirrhosis. Discovering novel biomarkers for risk stratification of HCC is paramount. We ex...
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Article
Open AccessImproved survival after treatments of patients with nonalcoholic fatty liver disease associated hepatocellular carcinoma
Worldwide, nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions and in parallel, hepatocellular carcinoma (HCC) has become one of the fastest growing cancers. Despite the rise in these dis...
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Article
Microbial Profiles of Cirrhosis in the Human Small Intestine
The aim of this review is to summarize the recent literature on associations of small intestinal microbial and bile acid profiles with liver cirrhosis and its complications.
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Article
Open AccessLipid levels in HIV-positive men receiving anti-retroviral therapy are not associated with copy number variation of reverse cholesterol transport pathway genes
The exacerbation of HIV-1 associated dyslipidemia seen in a subset of patients receiving anti-retroviral therapy suggests that genetic factors put these individuals at greater risk of cardiovascular disease. S...
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Article
Genetic variation at 8q24, family history of cancer, and upper gastrointestinal cancers in a Chinese population
Genetic variation at 8q24 is associated with prostate, bladder, breast, colorectal, thyroid, lung, ovarian, UADT, liver and stomach cancers. However, a role for variation at 8q24 in familial clustering of uppe...
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Article
Open AccessUltraviolet radiation exposure and HIV-associated non-Hodgkin lymphoma risk
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Open AccessRisk factors for squamous cell skin cancer in HIV
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Open AccessElevated serum levels of CXCL13 precede HIV-associated non-Hodgkin’s lymphoma
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Article
Open AccessSequence variation in the human transcription factor gene POU5F1
POU5F1 expression is required to maintain stem cell pluripotency and for primordial germ cells to retain proliferative capability in embryonic development. Recent evidence suggests that POU5F1 may also be a testi...
