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    Article

    YB-1 activating cascades as potential targets in KRAS-mutated tumors

    Y‑box binding protein‑1 (YB-1) is a multifunctional protein that is highly expressed in human solid tumors of various entities. Several cellular processes, e.g. cell cycle progression, cancer stemness and DNA dam...

    Shayan Khozooei, Soundaram Veerappan in Strahlentherapie und Onkologie (2023)

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    Open Access

    Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells

    Triple-negative breast cancer (TNBC) is associated with aggressiveness and a poor prognosis. Besides surgery, radiotherapy serves as the major treatment modality for TNBC. However, response to radiotherapy is ...

    Shayan Khozooei, Konstanze Lettau in Journal of Experimental & Clinical Cancer … (2022)