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Article
Open AccessRole of O-linked N-acetylglucosamine protein modification in oxidative stress-induced autophagy: a novel target for bone remodeling
O-linked N-acetylglucosamine protein modification (O-GlcNAcylation) is a dynamic post-translational modification (PTM) involving the covalent binding of serine and/or threonine residues, which regulates bone c...
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Article
Open AccessO-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology
O-linked N-acetylglucosamine (O-GlcNAc) protein modification (O-GlcNAcylation) is a critical post-translational modification (PTM) of cytoplasmic and nuclear proteins. O-GlcNAcylation levels are regulated by t...
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Article
Open AccessPrimary cutaneous anaplastic large-cell lymphoma resembling infratemporal space infection: a case report
Primary cutaneous anaplastic large-cell lymphoma (PC-ALCL) is a rare T-cell lymphoma belonging to the CD30 + T-cell lymphoproliferative disorders. The case of PC-ALCL in the temporal region is exceedingly rare...
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Article
Open AccessThe microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma
Autophagy is related to many cellular mechanisms and dysregulation of autophagy involves the pathological process in cancer. miR-10b activates autophagy, which promotes invasion and migration of OSCC. Its func...
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Article
Open AccessMiR-152-5p suppresses osteogenic differentiation of mandible mesenchymal stem cells by regulating ATG14-mediated autophagy
Osteoporosis affects the mandible resulting in bone loss. Though impairments are not life threatening, they affect a person's quality-of-life particularly vulnerable elderly. MicroRNAs (miRNAs) are novel regul...
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Article
Open AccessCirc-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas
Autophagy is an evolutionally conserved catabolic process that degrades cells to maintain homeostasis. Cisplatin-activated autophagy promotes the expression of circ-PKD2, which plays a role as a tumor suppress...
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Article
Open AccessThe RBP1–CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma
Retinol-binding protein 1 (RBP1) is involved in several physiological functions, including the regulation of the metabolism and retinol transport. Studies have shown that it plays an important role in the path...
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Article
Open AccessCirculating tumor cells undergoing EMT are poorly correlated with clinical stages or predictive of recurrence in hepatocellular carcinoma
Experimental and clinical studies have highlighted that circulating tumor cell (CTC) with phenotypic hallmarks of epithelial-mesenchymal transition (EMT) plays a critical role in the metastatic and recurrence ...
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Article
CBCT-based bone quality assessment in decompression of large odontogenic cystic lesions
Bone quality comprises bone mineral density and trabecular microstructure. The aim of this study was to explore the effectiveness of cone-beam computed tomography (CBCT) in evaluating bone quality of large odo...
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Chapter and Conference Paper
Method and System of Maize Hybridized Combination Based on Inbred SSR and Field Test
Molecular breeding is considered an important way to improve the breeding efficiency. But due to the deletion of data, method and instrument, molecular design breeding is basically at the concept stage, withou...
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Chapter and Conference Paper
An Automatic Counting Method of Maize Ear Grain Based on Image Processing
Corn variety testing is a process to pick and cultivate a high yield, disease resistant and outstandingly adaptive variety from thousands of corn hybrid varieties. In this process, we have to do a large number...
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Article
miR-21 modulates chemosensitivity of tongue squamous cell carcinoma cells to cisplatin by targeting PDCD4
Chemoresistance is a challenge for clinician in management of tongue cancer. Therefore, it is necessary to explore alternative therapeutic methods to overcome drug resistance. miRNAs are endogenous −22nt RNAs...
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Chapter and Conference Paper
Development of Information Support System for the Application of New Maize Variety Based on Smartphone
Assisted by mobile and information technologies, the risk of new maize variety application will be reduced and the efficiency will be enhanced significantly. According to the demands of new maize variety adopt...
