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Article

CHIP promotes the activation of NF-κB signaling through enhancing the K63-linked ubiquitination of TAK1

Transcriptional factor nuclear factor κB (NF-κB) can be activated by various intracellular or extracellular stimuli and its dysregulation leads to pathological conditions, such as neurodegenerative disorders, ...

Yuchun Liu, Yao Sun, Shaoming Han, Yanan Guo, Qingnan Tian… in Cell Death Discovery (2021)