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Article
Impact of lactate/albumin ratio on prognostic outcomes in patients with concomitant heart failure and chronic kidney disease
Previous studies have linked the lactate/albumin (L/A) ratio to poor outcomes in various conditions, but its connection to mortality in patients with both heart failure (HF) and chronic kidney disease (CKD) re...
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Article
Open AccessChanging of mechanical property and bearing capacity of strongly chlorine saline soil under freeze-thaw cycles
Freeze-thaw cycles and compactness are two critical factors that significantly affect the engineering properties and safety of building foundations, especially in seasonally frozen regions. This paper investig...
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Article
Hypoxia-induced SHMT2 protein lactylation facilitates glycolysis and stemness of esophageal cancer cells
Esophageal cancer (EC) is a familiar digestive tract tumor with highly lethal. The hypoxic environment has been demonstrated to be a significant factor in modulating malignant tumor progression and is strongly...
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Article
Open AccessCorrection: The high-risk features and effect of postoperative radiotherapy on survival for patients with surgically treated stage IIIA-N2 non-small cell lung cancer
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Article
Combinative predictive effect of left ventricular mass index, ratio of HDL and CRP for progression of chronic kidney disease in non-dialysis patient
This current study scrutinized the association among left ventricular mass index (LVMI), ratio of high-density lipoprotein (HDL) and C-reactive protein (CRP), and renal function. Furthermore, we examined the p...
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Article
Open AccessSHMT2 regulates esophageal cancer cell progression and immune Escape by mediating m6A modification of c-myc
In recent years, the role of altered cellular metabolism in tumor progression has attracted widespread attention. Related metabolic enzymes have also been considered as potential cancer therapeutic targets. Se...
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Article
Activation of β2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms
We previously reported that prolonged exposure to an enriched environment (EE) enhances hippocampal synaptic plasticity, with one of the significant mechanistic pathways being activation of β2-adrenergic receptor...
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Article
Open AccessPropensity score-matched analysis comparing hippocampus-avoidance whole-brain radiotherapy plus simultaneous integrated boost with hippocampus‑avoidance whole-brain radiotherapy alone for multiple brain metastases-a retrospective study in multiple institutions
The optimal treatment for multiple brain metastases has been recently controversially discussed.This study was aimed to explore the feasibility of Hippocampus-Avoidance Whole-Brain Radiotherapy plus a simultan...
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Article
Open AccessThe high-risk features and effect of postoperative radiotherapy on survival for patients with surgically treated stage IIIA-N2 non-small cell lung cancer
Although postoperative radiotherapy (PORT) could reduce the incidence of local recurrence in patients with IIIA-N2 non-small cell lung cancer (NSCLC), the role of PORT on survival in patients with surgically t...
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Article
Robust estimation for nonrandomly distributed data
In recent years, many methodologies for distributed data have been developed. However, there are two problems. First, most of these methods require the data to be randomly and uniformly distributed across diff...
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Article
Distributed statistical optimization for non-randomly stored big data with application to penalized learning
Distributed optimization for big data has recently attracted enormous attention. However, the existing algorithms are all based on one critical randomness condition, i.e., the big data are randomly distributed...
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Article
Degradation Mechanisms of Chloride Contaminated Cast-in-Situ Concrete Partially Exposed to Magnesium-Sulfate Combined Environment
Cast-in-situ concrete suffers complicated working conditions in sulfate-rich saline soil areas. Sulfate-magnesium combined attack can be encountered in heavy saline or salty lake areas. This study investigated...
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Article
Deep-hole axis deviation mechanism of weak stiffness small-diameter single-lip tool in low-frequency vibration-assisted drilling
Deep-hole manufacturing is widely applied in the aerospace, transportation, and mineral mining industry. The axis deviation of deep-hole is a manufacturing challenge, especially in the small-diameter weak stif...
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Article
Open AccessDynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity
In Parkinson’s disease and other synucleinopathies, the elevation of α-synuclein phosphorylated at Serine129 (pS129) is a widely cited marker of pathology. However, the physiological role for pS129 has remaine...
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Article
Potential Mechanism of LeTID Dynamic Behavior Dependent on Firing and Hydrogenation with Electron Injection
In recent years, the behavior of light and elevated temperature-induced degradation (LeTID) has seriously influence on the performance and stability of high efficiency passivated emitter and rear contact (PERC...
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Article
Bioactive human Alzheimer brain soluble Aβ: pathophysiology and therapeutic opportunities
The accumulation of amyloid-β protein (Aβ) plays an early role in the pathogenesis of Alzheimer’s disease (AD). The precise mechanism of how Aβ accumulation leads to synaptic dysfunction and cognitive impairme...
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Article
Infrared photon-assisted annealing for crystal engineering in perovskite solar cells
In this study, it was found that infrared-assisted annealing (IAA) was a novel and rapid method for growing of high-qualitied MAPbI3 films. Compared to traditional thermal annealing, this new strategy combined hi...
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Article
New insights into the relationship between capacity fading and sulfur loading and electrolyte/sulfur ratio obtained from Li–S pouch cell
High-energy density lithium-sulfur (Li–S) cells have been greatly studied due to the urgent requirements for advanced energy storage applications. During the past decades, many achievements have been obtained ...
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Article
Photo-induced hydrogenation and rapid cooling measure on dislocation clusters of multi-crystalline silicon PERC solar cells
The dislocations are the deep level defects with a negative impact on the multi-crystalline silicon (mc-Si) solar cells. Though potential mechanisms of dislocation formation on the silicon ingot have been stud...
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Article
Impurity mechanism of monocrystalline silicon PERC solar cells stimulated by prelight-induced degradation
Although the monocrystalline silicon (mono-Si)-passivated emitter and rear contact (PERC) solar cells have achieved incredible efficiency, they still can be further improved by hydrogenation. So the hydrogenat...