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Article
Novel decision tree models predict the overall survival of patients with submandibular gland cancer
While the accurate prediction of the overall survival (OS) in patients with submandibular gland cancer (SGC) is paramount for informed therapeutic planning, the development of reliable survival prediction mode...
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Article
Open AccessRadical innovation breakthroughs of biodegradation of plastics by insects: history, present and future perspectives
Insects damaging and penetrating plastic packaged materials has been reported since the 1950s. Radical innovation breakthroughs of plastic biodegradation have been initiated since the discovery of biodegradati...
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Article
Structure evolution at the gate-tunable suspended graphene–water interface
Graphitic electrode is commonly used in electrochemical reactions owing to its excellent in-plane conductivity, structural robustness and cost efficiency1,2. It serves as prime electrocatalyst support as well as ...
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Article
Benefit of [18F] FDG PET/CT in the diagnosis and salvage treatment of recurrent nasopharyngeal carcinoma
To compare PET/CT, MRI and ultrasonography in detecting recurrence of nasopharyngeal carcinoma and identify their benefit in staging, contouring and overall survival (OS).
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Article
Progress in Mechanism of Astragalus membranaceus and Its Chemical Constituents on Multiple Sclerosis
The primary chemical components of Astragalus membranaceus include polysaccharides, saponins, flavonoids, and amino acids. Recent studies have shown that Astragalus membranaceus has multiple functions, including ...
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Article
Open AccessA redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1
Anti-CRISPRs (Acrs) are natural inhibitors of bacteria’s CRISPR-Cas systems, and have been developed as a safeguard to reduce the off-target effects of CRISPR gene-editing technology. Acrs can directly bind to...
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Article
Open AccessRole of postoperative chemoradiotherapy in head and neck cancer without positive margins or extracapsular extension: a propensity score-matching analysis
The aim of this work was to determine whether patients with intermediate-risk head and neck squamous cell carcinoma (HNSCC) can benefit from postoperative chemoradiotherapy (POCRT).
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Article
Open AccessDevelopment and validation of radiologic scores for guiding individualized induction chemotherapy in T3N1M0 nasopharyngeal carcinoma
We aimed to develop and validate radiologic scores from [18F]FDG PET/CT and MRI to guide individualized induction chemotherapy (IC) for patients with T3N1M0 nasopharyngeal carcinoma (NPC).
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Article
Indirect approach for predicting cutting force coefficients and power consumption in milling process
Accurate energy consumption modeling is an essential prerequisite for sustainable manufacturing. Recently, cutting-power-based models have garnered significant attention, as they can provide more comprehensive...
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Article
Open AccessBenefit of [18F]-FDG PET/CT for treatment-naïve nasopharyngeal carcinoma
To test the advantages of positron emission tomography and computed tomography (PET/CT) for diagnosing lymph nodes and staging nasopharyngeal carcinoma and to investigate its benefits for survival and treatmen...
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Article
Open AccessBrain-derived neurotrophic factor gene variants and obesity in former smokers
From genome-wide association studies, brain-derived neurotrophic factor (BDNF) locus on chromosome 11 was the only SNP associated with both smoking and body mass index (BMI) in European, African and Asian populat...
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Article
Open AccessValidity and reliability of the simplified Chinese patient-reported outcomes version of the common terminology criteria for adverse events
The psychometric properties of the simplified Chinese version of the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) have not been assessed. Therefore, we ai...
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Article
Open AccessInhibition of Delta-like Ligand 4 enhances the radiosensitivity and inhibits migration in cervical cancer via the reversion of epithelial–mesenchymal transition
Concurrent chemoradiotherapy is the common first-line treatment for patients with advanced cervical cancer. However, radioresistance remains a major clinical challenge, which results in recurrence and poor sur...
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Biodegradation of Plastics in Tenebrio Genus (Mealworms)
Most petroleum-based plastics are resistant to biodegradation in the environment. Observation of damage, penetration, and ingestion of plastics by insects and their larvae lead to research on biodegradation of...
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Article
PGC-1α coordinates with Bcl-2 to control the cell cycle in U251 cells through reducing ROS
B-cell lymphoma 2 (Bcl-2) has a dual function, acting as both an oncogene and an anti-tumor gene. It is well known that Bcl-2 exerts its tumor promoting function through the mitochondrial pathway. However, the me...
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Article
Anti-folates potentiate bactericidal effects of other antimicrobial agents
Synergies between sulfonamides and other antimicrobial agents have long been reported, but the reason still remains unclear. Previously, Vilchèze et al. found that, sulfamethoxazole (SMX) could potentiate the bac...
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Article
Therapeutic Sesamol Attenuates Monocrotaline-Induced Sinusoidal Obstruction Syndrome in Rats by Inhibiting Matrix Metalloproteinase-9
We investigated the therapeutic effect of sesamol against monocrotaline-induced sinusoidal obstruction syndrome (SOS) in rats. Male Sprague–Dawley rats were gavaged with a single dose of monocrotaline (90 mg/k...
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Article
Aqueous Synthesis of CdTe/CdSe Core/Shell Quantum Dots as pH-Sensitive Fluorescence Probe for the Determination of Ascorbic Acid
By controlling the reflux time and the quantity of the shell materials, different sizes of thioglycollic acid (TGA) modified CdTe/CdSe core/shell quantum dots were synthesized in aqueous solution. This type of...
