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    Article

    Exercise preconditioning promotes myocardial GLUT4 translocation and induces autophagy to alleviate exhaustive exercise-induced myocardial injury in rats

    Exercise preconditioning (EP) is a line of scientific inquiry into the short-term biochemical mediators of cardioprotection in the heart. This study examined the involvement of autophagy induced by energy meta...

    Yuan-Pan Guo, Shan-Shan Pan, Tian-Ran Chen, Yue Huang in Journal of Molecular Histology (2023)

  2. Article

    Open Access

    Exercise preconditioning improves electrocardiographic signs of myocardial ischemic/hypoxic injury and malignant arrhythmias occurring after exhaustive exercise in rats

    Exercise preconditioning (EP) has a good myocardial protective effect. This study explored whether EP improves electrocardiographic (ECG) signs of myocardial ischemic/hypoxic injury and the occurrence of malig...

    Yuan-Pan Guo, Shan-Shan Pan in Scientific Reports (2022)

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    Article

    Late Exercise Preconditioning Regulates BNP Increasing to Assist the Cardioprotection via Up-Regulation of NPR-A and Down-Regulation of NPR-C in Rat Myocardium

    Late exercise preconditioning (LEP) is known to have a cardioprotection against myocardial injury induced by high-intensity exercise (HE). B-type natriuretic peptide (BNP) carries out the majority of its effec...

    Dong-Feng Wan, Zhe Hao, Yue Huang in International Journal of Peptide Research … (2021)

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    Article

    Comparison of myocardial ischemic/hypoxic staining techniques for evaluating the alleviation of exhaustive exercise-induced myocardial injury by exercise preconditioning

    Exercise preconditioning (EP) can alleviate myocardial ischemic/hypoxic injury by inducing endogenous cardioprotection. Hematoxylin–eosin (HE), hematoxylin-basic fuchsin-picric acid (HBFP), and chromotrope-2R ...

    Yue Huang, Shan- Shan Pan, Yuan-Pan Guo, Jia-Yin Wang in Journal of Molecular Histology (2021)

  5. Article

    Open Access

    Altered expression levels of autophagy-associated proteins during exercise preconditioning indicate the involvement of autophagy in cardioprotection against exercise-induced myocardial injury

    Exercise has been reported to induce autophagy. We hypothesized that exercise preconditioning (EP)-related autophagy in cardiomyocytes could be attributed to intermittent ischemia–hypoxia, allowing the heart t...

    Jian-Qi Yuan, Yang Yuan, Shan-Shan Pan, Ke Cai in The Journal of Physiological Sciences (2020)

  6. Article

    Cardioprotection of exercise preconditioning involving heat shock protein 70 and concurrent autophagy: a potential chaperone-assisted selective macroautophagy effect

    It has been confirmed that exercise preconditioning (EP) has a protective effect on acute cardiovascular stress. However, how Hsp70 participates in EP-induced cardioprotection is unknown. EP may involve Hsp70 ...

    Yang Yuan, Shan-Shan Pan, Yu-Jun Shen in The Journal of Physiological Sciences (2018)

  7. Article

    Elevated C-type natriuretic peptide elicits exercise preconditioning-induced cardioprotection against myocardial injury probably via the up-regulation of NPR-B

    To evaluate exercise preconditioning (EP)-induced cardioprotective effects against exercise-induced acute myocardial injury and investigate the alterations of C-type natriuretic peptide (CNP) and its specific ...

    Jiao Lu, Shan-Shan Pan in The Journal of Physiological Sciences (2017)

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    Article

    Stationary response of stochastically excited nonlinear systems with continuous-time Markov jump

    An approximate method for predicting the stationary response of stochastically excited nonlinear systems with continuous-time Markov jump is proposed. By using the stochastic averaging method, the original sys...

    Shan-shan Pan, Wei-qiu Zhu, Rong-chun Hu in Journal of Zhejiang University-SCIENCE A (2017)

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    Article

    Dynamics of a prey-predator system under Poisson white noise excitation

    The classical Lotka-Volterra (LV) model is a well-known mathematical model for prey-predator ecosystems. In the present paper, the pulse-type version of stochastic LV model, in which the effect of a random nat...

    Shan-Shan Pan, Wei-Qiu Zhu in Acta Mechanica Sinica (2014)

  10. Article

    Exercise preconditioning-induced late phase of cardioprotection against exhaustive exercise: possible role of protein kinase C delta

    The objective of this study was to investigate the late cardiac effect of exercise preconditioning (EP) on the exhaustive exercise-induced myocardial injury in rats and the role of protein kinase C (PKC) in EP...

    Zhe Hao, Shan-Shan Pan, Yu-Jun Shen, Jun Ge in The Journal of Physiological Sciences (2014)

  11. No Access

    Article

    Exercise preconditioning provides early cardioprotection against exhaustive exercise in rats: potential involvement of protein kinase C delta translocation

    The objective of this study was to investigate the early cardioprotective effect of exercise preconditioning (EP) on the exhaustive exercise-induced myocardial injury in rats and the role of protein kinase C d...

    Yu-Jun Shen, Shan-Shan Pan, Jun Ge, Zhe Hao in Molecular and Cellular Biochemistry (2012)

  12. Article

    Exercise preconditioning initiates late cardioprotection against isoproterenol-induced myocardial injury in rats independent of protein kinase C

    The objective of this study was to investigate the late cardioprotective effect of exercise preconditioning (EP) on isoproterenol (ISO)-induced myocardial injury in rats and the role of protein kinase C (PKC) ...

    Yu-Jun Shen, Shan-Shan Pan, Tao Zhuang in The Journal of Physiological Sciences (2011)

  13. No Access

    Article

    Bioremediation potential of spirulina: toxicity and biosorption studies of lead

    This study examines the possibility of using live spirulina to biologically remove aqueous lead of low concentration (below 50 mg/L) from wastewater. The spirulina cells were first immersed for seven days in f...

    Hong Chen, Shan-shan Pan in Journal of Zhejiang University-SCIENCE B (2005)