-
Article
Open AccessAssociation between Epstein-Barr virus infection and gastric cancer: a systematic review and meta-analysis
Numerous studies conducted over the past 30 years have pointed to the presence of Epstein–Barr virus (EBV) in gastric cancer samples. This study was aimed to provide a meta-analytic review of the prevalence of...
-
Article
HIV-1 integrase drug-resistance mutations in Iranian treatment-experienced HIV-1-infected patients
The latest class of antiretrovirals (ARVs), including integrase strand transfer inhibitors (INSTIs), has been demonstrated to be effective for antiretroviral therapy (ART). Despite all the distinguishing chara...
-
Article
Open AccessInhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine
Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing need for the development of novel, s...
-
Article
Molecular diagnosis of occult hepatitis C virus infection in Iranian injection drug users
Occult HCV infection (OCI) has been described as the presence of hepatitis C virus (HCV) genomic RNA in hepatocytes and/or peripheral blood mononuclear cell (PBMC) specimens and the lack of HCV genomic RNA and...
-
Article
Detection of HBV genome in the plasma and peripheral blood mononuclear cells of Iranian HBsAg negative patients with HIV infection: occult HBV infection
The presence of hepatitis B virus (HBV) DNA in the absence of traceable hepatitis B surface antigen (HBsAg) in the plasma specimen of patients is defined as occult HBV infection (OBI). This study aimed to dete...
-
Article
Investigation of the effects of a prevention of mother-to-child HIV transmission program among Iranian neonates
Human immunodeficiency virus (HIV) infection is mostly spreading in develo** countries. One of the most important pathways of HIV infection in these nations is the vertical route, from mother to infant. Ther...
-
Article
HIV-1 genetic diversity and transmitted drug resistance frequency among Iranian treatment-naive, sexually infected individuals
In recent years, the patterns of human immunodeficiency virus 1 (HIV-1) transmission in Iran have been changing gradually from drug injection to unprotected sexual contact. This study sought to investigate the...
-
Article
Merkel cell polyomavirus IgG antibody levels are associated with progression to AIDS among HIV-infected individuals
The association of Merkel cell polyomavirus (MCPyV) with Merkel cell carcinoma (MCC) in immunocompromised individuals has been revealed in a number of surveys. The study of MCPyV specific antibody titers and vira...
-
Article
Prevalence of occult hepatitis C virus infection in Iranian patients with beta thalassemia major
Occult hepatitis C virus infection (OCI) is a new pathological form of chronic hepatitis virus (HCV) infection characterized by the presence of HCV RNA in liver biopsy and/or peripheral blood mononuclear cell ...
-
Article
Merkel cell polyomavirus and human papillomavirus infections in cervical disease in Iranian women
Human papillomavirus (HPV) infection is a necessary cause of cervical neoplasia. Concomitant infection with other infectious agents has been demonstrated to be a cofactor for HPV-related cervical carcinogenesi...
-
Article
Prevalence of JC polyomavirus large T antigen sequences among Iranian patients with central nervous system tumors
The human neurotropic JC virus (JCV) is of significant interest due to its experimental neuro- oncogenic potential. In clinical samples from human central nervous system (CNS) tumors, detection of JCV sequence...
-
Article
Mutations in the NS5A gene of hepatitis C virus subtype 1b and response to peg-IFNα-2a/RBV combination therapy in Azerbaijani patients
Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease throughout the world. The presence of mutations in different regions of the HCV subtype 1b (HCV-1b) nonstructural 5A (NS5A)...