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Article
Open AccessPrevalence and genotype distribution of genital human papillomavirus infection in female sex workers in the world: a systematic review and meta-analysis
Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is th...
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Article
Open AccessAssociation between Epstein-Barr virus infection and gastric cancer: a systematic review and meta-analysis
Numerous studies conducted over the past 30 years have pointed to the presence of Epstein–Barr virus (EBV) in gastric cancer samples. This study was aimed to provide a meta-analytic review of the prevalence of...
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Article
HIV-1 integrase drug-resistance mutations in Iranian treatment-experienced HIV-1-infected patients
The latest class of antiretrovirals (ARVs), including integrase strand transfer inhibitors (INSTIs), has been demonstrated to be effective for antiretroviral therapy (ART). Despite all the distinguishing chara...
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Article
Open AccessInhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine
Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing need for the development of novel, s...
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Article
Molecular evidence of human papillomaviruses in the retinoblastoma tumor
Retinoblastoma tumor (RB) is one of the most prevalent ocular cancers among children. RB may be caused by inherited mutations in RB1 gene as well as some environmental risk factors. Human papillomaviruses (HPV) a...
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Article
Molecular diagnosis of occult hepatitis C virus infection in Iranian injection drug users
Occult HCV infection (OCI) has been described as the presence of hepatitis C virus (HCV) genomic RNA in hepatocytes and/or peripheral blood mononuclear cell (PBMC) specimens and the lack of HCV genomic RNA and...
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Article
Detection of HBV genome in the plasma and peripheral blood mononuclear cells of Iranian HBsAg negative patients with HIV infection: occult HBV infection
The presence of hepatitis B virus (HBV) DNA in the absence of traceable hepatitis B surface antigen (HBsAg) in the plasma specimen of patients is defined as occult HBV infection (OBI). This study aimed to dete...
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Article
Investigation of the effects of a prevention of mother-to-child HIV transmission program among Iranian neonates
Human immunodeficiency virus (HIV) infection is mostly spreading in develo** countries. One of the most important pathways of HIV infection in these nations is the vertical route, from mother to infant. Ther...
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Article
HIV-1 genetic diversity and transmitted drug resistance frequency among Iranian treatment-naive, sexually infected individuals
In recent years, the patterns of human immunodeficiency virus 1 (HIV-1) transmission in Iran have been changing gradually from drug injection to unprotected sexual contact. This study sought to investigate the...
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Article
Merkel cell polyomavirus IgG antibody levels are associated with progression to AIDS among HIV-infected individuals
The association of Merkel cell polyomavirus (MCPyV) with Merkel cell carcinoma (MCC) in immunocompromised individuals has been revealed in a number of surveys. The study of MCPyV specific antibody titers and vira...
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Article
Prevalence of occult hepatitis C virus infection in Iranian patients with beta thalassemia major
Occult hepatitis C virus infection (OCI) is a new pathological form of chronic hepatitis virus (HCV) infection characterized by the presence of HCV RNA in liver biopsy and/or peripheral blood mononuclear cell ...
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Article
Open AccessSNP haploty** technique for evaluation of MGP 5′ UTR power in osteoblast cells
Matrix Gla protein (MGP) is involved in calcium trafficking and arterial calcification. The aim of study was to investigate the role of three polymorphisms within the MGP gene promoter region on reporter gene ...
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Article
Merkel cell polyomavirus and human papillomavirus infections in cervical disease in Iranian women
Human papillomavirus (HPV) infection is a necessary cause of cervical neoplasia. Concomitant infection with other infectious agents has been demonstrated to be a cofactor for HPV-related cervical carcinogenesi...
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Article
Prevalence of JC polyomavirus large T antigen sequences among Iranian patients with central nervous system tumors
The human neurotropic JC virus (JCV) is of significant interest due to its experimental neuro- oncogenic potential. In clinical samples from human central nervous system (CNS) tumors, detection of JCV sequence...
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Article
Mutations in the NS5A gene of hepatitis C virus subtype 1b and response to peg-IFNα-2a/RBV combination therapy in Azerbaijani patients
Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease throughout the world. The presence of mutations in different regions of the HCV subtype 1b (HCV-1b) nonstructural 5A (NS5A)...