4 Result(s)
within
Seungyeon Ryu
English
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Article
Open AccessThe miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics
Senescent cells exhibit a diverse spectrum of changes in their morphology, proliferative capacity, senescence-associated secretory phenotype (SASP) production, and mitochondrial homeostasis. These cells often ...
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Article
Open AccessImpact of media compositions and culture systems on the immunophenotypes of patient-derived breast cancer cells
Heterogeneous tumor cells are thought to be a significant factor in the failure of endocrine therapy in estrogen receptor-positive (ER+) cancers. Culturing patient-derived breast cancer cells (PDBCCs) provides...
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Article
Open AccessRNA binding protein HuD mediates the crosstalk between β cells and islet endothelial cells by the regulation of Endostatin and Serpin E1 expression
RNA binding protein HuD plays essential roles in gene expression by regulating RNA metabolism, and its dysregulation is involved in the pathogenesis of several diseases, including tumors, neurodegenerative dis...
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Article
Open AccessLoss of RNA binding protein HuD facilitates the production of the senescence-associated secretory phenotype
HuD, an RNA binding protein, plays a role in the regulation of gene expression in certain types of cells, including neuronal cells and pancreatic β-cells, via RNA metabolism. Its aberrant expression is associa...
