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Open AccessThe miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics
Senescent cells exhibit a diverse spectrum of changes in their morphology, proliferative capacity, senescence-associated secretory phenotype (SASP) production, and mitochondrial homeostasis. These cells often ...
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Article
Open AccessAuthor Correction: The miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
RNA binding protein HuD contributes to β-cell dysfunction by impairing mitochondria dynamics
Imbalanced mitochondrial dynamics in pancreatic β-cells contributes to β-cell dysfunction in diabetes; however, the molecular mechanisms underlying mitochondrial dynamics in the pathology of diabetes are not f...
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Article
Open AccessmicroRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression
Acquisition of resistance to anti-cancer drugs is a significant obstacle to effective cancer treatment. Although several efforts have been made to overcome drug resistance in cancer cells, the detailed mechani...
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Article
Open AccessThe miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells
MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression by suppressing translation or facilitating mRNA decay. Differential expression of miRNAs is involved in the pathogenesis of...
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Article
T-cell-restricted intracellular antigen 1 facilitates mitochondrial fragmentation by enhancing the expression of mitochondrial fission factor
Mitochondrial morphology is dynamically regulated by the formation of small fragmented units or interconnected mitochondrial networks, and this dynamic morphological change is a pivotal process in normal mitoc...
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Article
Open AccessmiR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor
Mitochondrial morphology is dynamically regulated by forming small, fragmented units or interconnected networks, and this is a pivotal process that is used to maintain mitochondrial homeostasis. Although dysre...