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  1. Article

    Open Access

    The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics

    Senescent cells exhibit a diverse spectrum of changes in their morphology, proliferative capacity, senescence-associated secretory phenotype (SASP) production, and mitochondrial homeostasis. These cells often ...

    Hyosun Tak, Seongho Cha, Youlim Hong, Myeongwoo Jung, Seungyeon Ryu in Cell Death & Disease (2024)

  2. Article

    Open Access

    Author Correction: The miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Hoin Kang, Jun Gi Rho, Chongtae Kim, Hyosun Tak, Hee** Lee in Scientific Reports (2021)

  3. No Access

    Article

    RNA binding protein HuD contributes to β-cell dysfunction by impairing mitochondria dynamics

    Imbalanced mitochondrial dynamics in pancreatic β-cells contributes to β-cell dysfunction in diabetes; however, the molecular mechanisms underlying mitochondrial dynamics in the pathology of diabetes are not f...

    Youlim Hong, Hyosun Tak, Chongtae Kim, Hoin Kang in Cell Death & Differentiation (2020)

  4. Article

    Open Access

    microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression

    Acquisition of resistance to anti-cancer drugs is a significant obstacle to effective cancer treatment. Although several efforts have been made to overcome drug resistance in cancer cells, the detailed mechani...

    Hee** Lee, Chongtae Kim, Hoin Kang, Hyosun Tak in Experimental & Molecular Medicine (2017)

  5. Article

    Open Access

    The miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells

    MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression by suppressing translation or facilitating mRNA decay. Differential expression of miRNAs is involved in the pathogenesis of...

    Hoin Kang, Jun Gi Rho, Chongtae Kim, Hyosun Tak, Hee** Lee in Scientific Reports (2017)

  6. Article

    T-cell-restricted intracellular antigen 1 facilitates mitochondrial fragmentation by enhancing the expression of mitochondrial fission factor

    Mitochondrial morphology is dynamically regulated by the formation of small fragmented units or interconnected mitochondrial networks, and this dynamic morphological change is a pivotal process in normal mitoc...

    Hyosun Tak, Jung Woo Eun, Jihye Kim, So Jung Park in Cell Death & Differentiation (2017)

  7. Article

    Open Access

    miR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor

    Mitochondrial morphology is dynamically regulated by forming small, fragmented units or interconnected networks, and this is a pivotal process that is used to maintain mitochondrial homeostasis. Although dysre...

    Hyosun Tak, Jihye Kim, Aravinth Kumar Jayabalan in Experimental & Molecular Medicine (2014)