-
Article
Genetic variation in the cag pathogenicity island of Helicobacter pylori strains detected from gastroduodenal patients in Thailand
There is a lack of evidence of genetic variation in the Helicobacter pylori cag-PAI in Thailand, a region with the low incidence of gastric cancer. To clarify this issue, variation in the H. pylori cag-PAI in str...
-
Article
Novel nuclear targeting coiled-coil protein of Helicobacter pylori showing Ca2+-independent, Mg2+-dependent DNase I activity
HP0059, an uncharacterized gene of Helicobacter pylori, encodes a 284-aa-long protein containing a nuclear localization sequence (NLS) and multiple leucine-rich heptad repeats. Effects of HP0059 proteins in human...
-
Article
Morphological changes in human gastric epithelial cells induced by nuclear targeting of Helicobacter pylori urease subunit A
Nuclear targeting of bacterial proteins and their pathological effects on host cells are an emerging pathogenic mechanism in bacteria. We have previously reported that urease subunit A (UreA) of Helicobacter pylo...
-
Article
An easy way for the rapid purification of recombinant proteins from Helicobacter pylori using a newly designed expression vector
We constructed a H. pylori expression vector which consisted of both a His-tag and a GST tag as purification tools for recombinant protein and a chloramphenicol resistant cat gene as a reporter. The backbone of t...
-
Article
Profiling of the bacteria responsible for pyogenic liver abscess by 16S rRNA gene pyrosequencing
Pyogenic liver abscess (PLA) is a severe disease with considerable mortality and is often polymicrobial. Understanding the pathogens that cause PLA is the basis for PLA treatment. Here, we profiled the bacteri...
-
Article
Erratum to: Genetic organization and conjugal plasmid DNA transfer of pHP69, a plasmid from a Korean isolate of Helicobacter pylori
-
Article
Genetic organization and conjugal plasmid DNA transfer of pHP69, a plasmid from a Korean isolate of Helicobacter pylori
We isolated pHP69, a 9,153 bp plasmid from Helicobacter pylori with a 33.98% (G+C) content. We identified 11 open reading frames (ORFs), including replication initiation protein A (repA), fic (cAM...
-
Article
Effects of Helicobacter pylori γ-Glutamyltranspeptidase on Apoptosis and Inflammation in Human Biliary Cells
Several studies have reported the presence of H. pylori in individuals with hepatobiliary diseases, but in vitro and in vivo studies are still needed. Here, we determined the effects of H. pylori γ-glutamyltransp...
-
Article
Role of cagA-Positive Helicobacter pylori on Cell Proliferation, Apoptosis, and Inflammation in Biliary Cells
The pathogenesis of Helicobacter pylori in the human hepatobiliary system has not been clearly elucidated. We compared the effects of H. pylori cagA+ and cagA− mutant strains on cell pr...
-
Article
Antibacterial and immuno-modulatory activity of ethanol extracts from Lespedeza sp. during Helicobacter pylori infections
Chemical therapeutics targeted against H. pylori may lead to host toxicity and pathogen eradication failures. In this study, ethanolic extracts from five Lespedeza sp. plants were shown to inhibit the gastric-pat...
-
Article
Analyses of route Bc equal channel angular pressing and post-equal channel angular pressing behavior by the finite element method
Equal channel angular pressing (ECAP) process provides an efficient procedure for achieving ultrafine grained microstructures with excellent mechanical properties in metallic materials. In this article, a simu...
-
Article
Helicobacter pylori γ-glutamyltranspeptidase induces cell cycle arrest at the G1-S phase transition
In our previous study, we showed that Helicobacter pylori γ-glutamyltranspeptidase (GGT) is associated with H. pylori-induced apoptosis through a mitochondrial pathway. To better understand the role of GGT in apo...
-
Article
Analysis of heat transfer in hot rolled coils for optimum condition of forced cooling
A new equation was proposed to investigate the heat transfer in the hot rolled coils by taking account of the variation of contact between coiled layers. The proposed equation was represented by the equivalent...
-
Article
Effects of centerline macrosegregation on necking of P-added extra low carbon steel sheet
Effects of centerline macrosegregation on necking was examined by the stretching experiment for cold rolled P-added extra low carbon steel sheets. The centerline macrosegregated zone containing high concentrat...
