1 Result(s)

Article

Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear proteins

Targeted protein degradation is a powerful tool in determining the function of specific proteins or protein complexes. We fused nanobodies to SPOP, an adaptor protein of the Cullin-RING E3 ubiquitin ligase com...

Yeong Ju Shin, Seung Kyun Park, Yoo Jung Jung, Ye Na Kim, Ki Sung Kim… in Scientific Reports (2015)