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Article

Enhanced anti-metastatic bioactivity of an IGF-TRAP re-engineered to improve physicochemical properties

The insulin-like growth factor (IGF) axis has been implicated in the progression of malignant disease and identified as a clinically important therapeutic target. Several IGF-1 receptor (IGF-1R) targeting drug...

George Vaniotis, Serge Moffett, Traian Sulea, Ni Wang, S. Mehdy Elahi… in Scientific Reports (2018)