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  1. Article

    Open Access

    A novel patient-derived immortalised cell line of myxofibrosarcoma: a tool for preclinical drugs testing and the generation of near-patient models

    Myxofibrosarcoma is a rare malignant soft tissue sarcoma characterised by multiple local recurrence and can become of higher grade with each recurrence. Consequently, myxofibrosarcoma represents a burden for p...

    Ania Naila Guerrieri, Chiara Bellotti, Marianna Penzo, Marta Columbaro… in BMC Cancer (2023)

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    Article

    Evaluation of TP53 Pro72Arg and MDM2 SNP285–SNP309 polymorphisms in an Italian cohort of LFS suggestive patients lacking identifiable TP53 germline mutations

    Li-Fraumeni syndrome (LFS) is a rare genetic cancer predisposition disease, partly determined by the presence of a TP53 germline mutation; lacking thereof, in presence of a typical LFS phenotype, defines a wide g...

    Francesca Ponti, Serena Corsini, Maria Gnoli, Elena Pedrini… in Familial Cancer (2016)