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  1. No Access

    Article

    A chitosan/alginate coated nano-liposome to improve intestinal absorption of curcumin for oral administration

    Attempts to improve low absorption and rapid metabolic conversion of curcumin were made by develo** curcumin-loaded bilayer nanoliposomes coated with chitosan and alginate for intestinal-specific drug delive...

    Gi-Hyun Jang, Yu-Mi Kim, Do-Hyeon Kim, Ji-Won Shin… in Food Science and Biotechnology (2024)

  2. Article

    Open Access

    The clinical impact of drug-induced hepatotoxicity on anti-tuberculosis therapy: a case control study

    There are limited data available on whether drug-induced hepatotoxicity (DIH) affects the clinical outcomes of tuberculosis (TB) treatment. We explored the effects of DIH on the clinical course and outcomes of...

    ** Hwa Song, Seo-Young Yoon, Tae Yun Park, Eun Young Heo… in Respiratory Research (2019)

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  3. Article

    Open Access

    Deflection induced cellular focal adhesion and anisotropic growth on vertically aligned silicon nanowires with differing elasticity

    Cellular adhesion and growth on substrates with differing surface topography are known to induce unusual cell behaviors. Here, we investigated the adhesion and growth of human embryonic kidney 293T cells on ve...

    Yi-Seul Park, Seo Young Yoon, Jeong Su Park, ** Seok Lee in NPG Asia Materials (2016)

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  4. No Access

    Article

    Alleviating effects of Opuntia ficus indica extracts on psychomotor alterations induced by ethanol in rats

    Effects of Opuntia ficus indica (OFI) extracts on ethanol-induced psychomotor alterations were studied using Sprague-Dawley rats orally administered 4 g/kg of ethanol (EtOH group) or distilled water (control grou...

    Irene Joy I. dela Peña, Seo Young Yoon, Hee ** Kim… in Food Science and Biotechnology (2014)

  5. No Access

    Article

    Luteolin mediates the antidepressant-like effects of Cirsium japonicum in mice, possibly through modulation of the GABAA receptor

    Cirsium japonicum (CJ) has been shown to possess antidepressant-like properties. In the present study, we sought to identify which constituent of CJ might be responsible for its antidepressant ef...

    June Bryan I. de la Peña, Chong Ah Kim, Hye Lim Lee… in Archives of Pharmacal Research (2014)

  6. No Access

    Article

    The involvement of magnoflorine in the sedative and anxiolytic effects of Sinomeni Caulis et Rhizoma in mice

    The present study seeks to evaluate the sedative and anxiolytic effects of the 70 % ethanol extract of Sinomeni Caulis et Rhizoma (SR). The extract was orally administered to mice at dosages of 25, 50, 100, 200 o...

    June Bryan I. de la Peña, Hye Lim Lee, Seo Young Yoon… in Journal of Natural Medicines (2013)

  7. No Access

    Article

    The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice

    We previously reported that oroxylin A, a γ-aminobutyric acid A (GABAA) receptor antagonist, ameliorates drugs-induced memory impairments. We synthesized several oroxylin A derivatives in efforts to find a substa...

    **aotong Liu, Sung In Hong, Se ** Park… in Archives of Pharmacal Research (2013)

  8. No Access

    Article

    Oroxylin A improves attention deficit hyperactivity disorder-like behaviors in the spontaneously hypertensive rat and inhibits reuptake of dopamine in vitro

    In previous studies we have demonstrated that the γ-aminobutryic acid-A (GABA-A) receptor antagonist oroxylin A has an awakening effect and it also represses ADHD-like behaviors (hyperactivity, impulsivity and...

    Seo Young Yoon, Ike dela Peña, Sung Mok Kim, Tae Sun Woo… in Archives of Pharmacal Research (2013)

  9. No Access

    Article

    Methylphenidate treatment in the spontaneously hypertensive rat: influence on methylphenidate self-administration and reinstatement in comparison with Wistar rats

    Methylphenidate is a psychostimulant given for extended periods of time as a treatment of attention-deficit/hyperactivity disorder (ADHD). The long-term effects of the drug are not yet known, and it is specula...

    Ike dela Peña, Seo Young Yoon, Jong Chan Lee, June Bryan dela Peña… in Psychopharmacology (2012)

  10. No Access

    Article

    Is the anti-stress effect of vitamin C related to adrenal gland function in rat?

    The aim of this study was to investigate whether vitamin C influences the stress response system of the adrenal gland. Adrenalectomized (ADX) rats and non-ADX rats were administered vitamin C and were subjecte...

    Ji Young Choi, Ike Campomayor dela Peña, Seo Young Yoon… in Food Science and Biotechnology (2011)

  11. No Access

    Article

    Vitamin C supplementation alleviates electroshock stress but not restraint stress in ICR mice

    The aim of this study was to investigate what kind of stress vitamin C could alleviate. Experiments were performed using male ICR mice. Vitamin C (1, 5, 25, and 100 mg/kg) was administered orally daily for 7 d...

    Ji Young Choi, Yoon Jung Choi, Ike Campomayor dela Peña… in Food Science and Biotechnology (2010)

  12. No Access

    Article

    Inhibition of intestinal motility by the putative BKCa channel opener LDD175

    LDD175 (4-chloro-7-trifluoromethyl-10H-benzo[4,5]furo[3,2-b]indole-1-carboxylic acid) is a benzofuroindole compound characterized previously as a potent opener of the large conductance calcium activated (BKCa) ch...

    Ike Campomayor dela Peña, Seo Young Yoon, Sung Mok Kim… in Archives of Pharmacal Research (2009)