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Article
Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes
Paracrine ATP release by erythrocytes has been shown to regulate endothelial cell function via purinergic signaling, and this erythoid-endothelial signaling network is pathologically dysregulated in sickle cel...
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Article
Open AccessAuthor Correction: Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21491-y
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Article
Open AccessAdaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand
Plasmodium species are frequently host-specific, but little is currently known about the molecular factors restricting host switching. This is particularly relevant for P. falciparum, the only known human-infecti...
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Article
Open AccessAncient human sialic acid variant restricts an emerging zoonotic malaria parasite
Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are sialylated....
