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  1. No Access

    Article

    Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation

    Obesity induces chronic inflammation resulting in insulin resistance and metabolic disorders. Cold exposure can improve insulin sensitivity in humans and rodents, but the mechanisms have not been fully elucida...

    Satoru Sugimoto, Hebe Agustina Mena, Brian E. Sansbury, Shio Kobayashi in Nature Metabolism (2022)

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    Protocol

    Signaling Lipidomic Analysis of Thermogenic Adipocytes

    Brown adipose tissue is a thermogenic organ that possesses anti-diabetic and anti-obesogenic potential. There has recently been growing interest on the secretory role of brown adipose tissue in regulating whol...

    Sean D. Kodani, Valerie Bussberg, Niven R. Narain in Brown Adipose Tissue (2022)

  3. Article

    Open Access

    Combustion-derived flame generated ultrafine soot generates reactive oxygen species and activates Nrf2 antioxidants differently in neonatal and adult rat lungs

    Urban particulate matter (PM) has been epidemiologically correlated with multiple cardiopulmonary morbidities and mortalities, in sensitive populations. Children exposed to PM are more likely to develop respir...

    Jackie KW Chan, Jessica G Charrier, Sean D Kodani in Particle and Fibre Toxicology (2013)