44 Result(s)

Article

Action-potential propagation gated by an axonal I_A-like K⁺ conductance in hippocampus

Integration of membrane-potential changes is traditionally reserved for neuronal somatodendritic compartments. Axons are typically considered to transmit reliably the result of this integration, the action pot...

Dominique Debanne, Nathalie C. Guérineau, Beat H. Gähwiler, Scott M. Thompson in Nature (1997)

Article

Lesion-induced axonal sprouting and hyperexcitability in the hippocampus in vitro: Implications for the genesis of posttraumatic epilepsy

The delayed development of recurring seizures is a common consequence of traumatic head injury; the cause of such epilepsy is unknown. We demonstrate here that transection of the mature axons of CA3 pyramidal ...

R. Anne Mckinney, Dominique Debanne, Beat H. Gähwiler, Scott M. Thompson in Nature Medicine (1997)

Article

Ephrins keep dendritic spines in shape

The EphB ephrin receptors are involved in synapse formation. New work now implicates the EphA family, as glial ephrin3A activates the EphA4 receptor on dendritic spines to stabilize spine shape.

Scott M. Thompson in Nature Neuroscience (2003)

Article

Activity-dependent activation of presynaptic protein kinase C mediates post-tetanic potentiation

Vesicle exocytosis is mediated by the complex interaction between synaptic vesicle and plasma membrane proteins, many of which are substrates for protein kinases^1,2,3. Exogenous protein kinase activators increase...

Darrin H Brager, **ang Cai, Scott M Thompson in Nature Neuroscience (2003)

Article

Secret of synapse specificity

How does the brain organize all of the information stored in memory? On the basis of a state-of-the-art imaging study of neuronal activity in real time, the answer seems to be, through specificity in space and...

Scott M. Thompson, Hayley A. Mattison in Nature (2009)

Article

AS30D Model of Hepatocellular Carcinoma: Tumorigenicity and Preliminary Characterization by Imaging, Histopathology, and Immunohistochemistry

This study was designed to determine the tumorigenicity of the AS30D HCC cell line following orthotopic injection into rat liver and preliminarily characterize the tumor model by both magnetic resonance imagin...

Scott M. Thompson, Matthew R. Callstrom… in CardioVascular and Interventional Radiology (2013)

Article

Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression

The authors find that serotonin, acting through 5-HT_1B receptors, potentiates temporoammonic pathway–to–CA1 cell excitatory synapses in the hippocampus. Chronic unpredictable stress increased the magnitude of thi...

**ang Cai, Angy J Kallarackal, Mark D Kvarta, Sasha Goluskin… in Nature Neuroscience (2013)

Article

Role for Putative Hepatocellular Carcinoma Stem Cell Subpopulations in Biological Response to Incomplete Thermal Ablation: In Vitro and In Vivo Pilot Study

To investigate the potential role for CD44⁺ and CD90⁺ hepatocellular carcinoma (HCC) cellular subpopulations in biological response to thermal ablation-induced heat stress.

Scott M. Thompson, Matthew R. Callstrom… in CardioVascular and Interventional Radiology (2014)

Article

Mechanical Properties and Microstructural Features of Direct Laser-Deposited Ti-6Al-4V

Direct laser deposition (DLD) is a means to additively manufacture metallic, functional parts via blown powder (or wire) and in situ laser delivery. Despite the various research efforts in characterization of ...

Linkan Bian, Scott M. Thompson, Nima Shamsaei in JOM (2015)

Article

Initial Results of Image-Guided Percutaneous Ablation as Second-Line Treatment for Symptomatic Vascular Anomalies

The purpose of this study was to determine the feasibility, safety, and early effectiveness of percutaneous image-guided ablation as second-line treatment for symptomatic soft-tissue vascular anomalies (VA).

Scott M. Thompson, Matthew R. Callstrom… in CardioVascular and Interventional Radiology (2015)

Article

Understanding the Microstructure Formation of Ti-6Al-4V During Direct Laser Deposition via In-Situ Thermal Monitoring

Understanding the thermal phenomena associated with direct laser deposition (DLD) is an important step toward obtaining ‘process–property–performance’ relationships for various designed parts and materials, as...

Garrett J. Marshall, W. Joseph Young II, Scott M. Thompson, Nima Shamsaei… in JOM (2016)

Article

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

Major depressive disorder affects around 16 per cent of the world population at some point in their lives. Despite the availability of numerous monoaminergic-based antidepressants, most patients require severa...

Panos Zanos, Ruin Moaddel, Patrick J. Morris, Polymnia Georgiou… in Nature (2016)

Article

Selective Parathyroid Hormone Venous Sampling in Patients with Persistent or Recurrent Primary Hyperparathyroidism and Negative, Equivocal or Discordant Noninvasive Imaging

In patients with persistent (P-PHPT) or recurrent (R-PHPT) primary hyperparathyroidism, preoperative localization is important. Selective parathyroid hormone venous sampling (sPVS) is an invasive technique tha...

Philip Y. Sun, Scott M. Thompson, James C. Andrews… in World Journal of Surgery (2016)

Article

MRI-guided Wire Localization Surgical Biopsy in an Adolescent Patient with a Difficult to Diagnose Case of Lymphoma

A 17-year-old previously healthy female presented with a progressive soft tissue infiltrative process involving the neck and thorax. Extensive diagnostic evaluation including multiple imaging, laboratory, and ...

Scott M. Thompson, Krzysztof R. Gorny… in CardioVascular and Interventional Radiology (2017)

Article

Microstructure, Fatigue Behavior, and Failure Mechanisms of Direct Laser-Deposited Inconel 718

Inconel 718 is considered to be a superalloy with a series of superior properties such as high strength, creep resistance, and corrosion resistance at room and elevated temperatures. Additive manufacturing (A...

Alex S. Johnson, Shuai Shao, Nima Shamsaei, Scott M. Thompson, Linkan Bian in JOM (2017)

Article

Zanos et al. reply

Panos Zanos, Ruin Moaddel, Patrick J. Morris, Polymnia Georgiou… in Nature (2017)

Article

Convergent Mechanisms Underlying Rapid Antidepressant Action

Traditional pharmacological treatments for depression have a delayed therapeutic onset, ranging from several weeks to months, and there is a high percentage of individuals who never respond to treatment. In co...

Panos Zanos, Scott M. Thompson, Ronald S. Duman, Carlos A. Zarate Jr.… in CNS Drugs (2018)

Article

Safety and Effectiveness of Palliative Tunneled Peritoneal Drainage Catheters in the Management of Refractory Malignant and Non-malignant Ascites

To determine the safety and effectiveness of tunneled peritoneal catheters in the management of refractory malignant and non-malignant ascites.

Jennifer A. Knight, Scott M. Thompson… in CardioVascular and Interventional Radiology (2018)