-
Article
Update on Percutaneous Ablation for Sarcoma
To provide an update on the current state of percutaneous thermal ablation in the treatment of sarcoma.
-
Article
Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder
The serotonin deficit hypothesis explanation for major depressive disorder (MDD) has persisted among clinicians and the general public alike despite insufficient supporting evidence. To combat rising mental he...
-
Article
Open AccessCommon design and data elements on rectal artery embolization for treatment of symptomatic internal hemorrhoidal disease: an interactive systematic review of clinical trials
Internal hemorrhoids (IH) is a common medical condition that can result in morbidity secondary to bleeding and discomfort. Treatment for IH has traditionally consisted of dietary and conservative medical manag...
-
Article
Open AccessChemogenetic activation of CRF neurons as a model of chronic stress produces sex-specific physiological and behavioral effects
Trauma and chronic stress exposure are the strongest predictors of lifetime neuropsychiatric disease presentation. These disorders often have significant sex biases, with females having higher incidences of af...
-
Article
Modulators of GABAA receptor-mediated inhibition in the treatment of neuropsychiatric disorders: past, present, and future
The predominant inhibitory neurotransmitter in the brain, γ-aminobutyric acid (GABA), acts at ionotropic GABAA receptors to counterbalance excitation and regulate neuronal firing. GABAA receptors are heteropentam...
-
Article
Plasticity of synapses and reward circuit function in the genesis and treatment of depression
What changes in brain function cause the debilitating symptoms of depression? Can we use the answers to this question to invent more effective, faster acting antidepressant drug therapies? This review provides...
-
Article
Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor
We show that the sex of human experimenters affects mouse behaviors and responses following administration of the rapid-acting antidepressant ketamine and its bioactive metabolite (2R,6R)-hydroxynorketamine. Mice...
-
Article
MELD-Na > 16 is associated with high peri-procedural and short-term mortality in patients with ruptured hepatocellular carcinoma treated with emergent transarterial embolization
To evaluate prognostic factors associated with peri-procedural (30 days) and short-term (90 days) mortality in the United States cohort of patients following emergent transarterial embolization for ruptured he...
-
Article
Toolkit for young professionals: how to get involved in the society of abdominal radiology—workshops, disease focus panels, emerging technology committees, and more
The Society of Abdominal Radiology (SAR) has grown rapidly in the last decade and with growth comes opportunity. The purpose of this article is to highlight the many potential ways in which early career radiol...
-
Article
Long-term renal function outcomes after renal cryoablation complicated by major hemorrhage requiring selective transarterial embolization
To determine long-term renal function outcomes after renal cryoablation complicated by major hemorrhage requiring transarterial embolization compared to patients who underwent uncomplicated renal cryoablation ...
-
Article
Correction: Optimizing psychedelic compounds for neuropsychiatric therapy
-
Article
Optimizing psychedelic compounds for neuropsychiatric therapy
-
Article
Pubertal adversity alters chromatin dynamics and stress circuitry in the pregnant brain
Women who have experienced adverse childhood events (ACEs) around puberty are at the greatest risk for neuropsychiatric disorders across the lifespan. This population is exceptionally vulnerable to neuropsychi...
-
Article
Experimental Analysis of Atypically Long Finned Oscillating Heat Pipe for Ventilation Waste Heat Recovery Application
Oscillating heat pipes (OHP) which are constructed from a serpentine-arranged capillary tube possess a desirable aerodynamic form factor and provide for relatively high heat transfer rates via cyclic evaporati...
-
Chapter
Fibrolamellar Carcinoma
Fibrolamellar carcinoma (FLC) is a rare primary liver cancer that arises in a background of normal liver, most commonly in teenagers and young adults. FLC has been shown to be induced by a deletion of chromoso...
-
Chapter
Soft Tissue Sarcoma (STS)
Image-guided thermal ablative therapies offer a therapeutic option for primary and metastatic soft tissue sarcoma as an adjunct or alternative to other focal therapies, such as surgery or radiation therapy, wh...
-
Chapter
Cholangiocarcinoma
Cholangiocarcinoma (CCA) is most strongly associated with risk factors characterized by chronic inflammatory states. However, most CCAs are sporadic, with no identifiable risk factors. In this chapter, we prov...
-
Article
(2R,6R)-hydroxynorketamine rapidly potentiates hippocampal glutamatergic transmission through a synapse-specific presynaptic mechanism
Preclinical studies indicate that (2R,6R)-hydroxynorketamine (HNK) retains the rapid and sustained antidepressant-like actions of ketamine, but is spared its dissociative-like properties and abuse potential. Whil...
-
Article
The critical importance of basic animal research for neuropsychiatric disorders
-
Article
PET Imaging of Hepatocellular Carcinoma
Positron emission tomography has not traditionally played a major role in the evaluation of hepatocellular carcinoma (HCC). Owing to high background liver uptake and molecular mechanisms within HCC lesions, up...