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Reward behaviour is regulated by the strength of hippocampus–nucleus accumbens synapses
Reward drives motivated behaviours and is essential for survival, and therefore there is strong evolutionary pressure to retain contextual information about rewarding stimuli. This drive may be abnormally stro...
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Zanos et al. reply
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Article
NMDAR inhibition-independent antidepressant actions of ketamine metabolites
Major depressive disorder affects around 16 per cent of the world population at some point in their lives. Despite the availability of numerous monoaminergic-based antidepressants, most patients require severa...
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Article
Secret of synapse specificity
How does the brain organize all of the information stored in memory? On the basis of a state-of-the-art imaging study of neuronal activity in real time, the answer seems to be, through specificity in space and...
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Erratum: Action-potential propagation gated by an axonal IA-like K+conductance in hippocampus
Nature 389, 286–289 (1997) Lüscher et al.1 have not shown that action potential propagation is normally reliable, as was inadvertently implied in our Letter. Their study demonstrates rather that action potenti...
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Article
Action-potential propagation gated by an axonal IA-like K+ conductance in hippocampus
Integration of membrane-potential changes is traditionally reserved for neuronal somatodendritic compartments. Axons are typically considered to transmit reliably the result of this integration, the action pot...