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Article
Fanconi syndrome with karyomegalic interstitial nephritis after ifosfamide treatment for osteosarcoma: a case report
Patients with ifosfamide-induced renal damage present with Fanconi syndrome. Karyomegalic nephropathy/interstitial nephritis (KNIN) is a rare form of chronic tubulo-interstitial nephritis that was initially co...
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Article
Frailty and dialysis initiation in the super-elderly
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Article
Open AccessPrognostic factors of IgA nephropathy presenting with mild proteinuria at the time of diagnosis (a multicenter cohort study)
Clinical factors affecting renal prognosis in patients with immunoglobulin A nephropathy (IgAN) and low urinary protein excretion (U-Prot) remain unclear. This study evaluated such factors in patients with cli...
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Article
Open AccessGranulomatous interstitial nephritis with CTLA-4 haploinsufficiency: a case report
Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential inhibitory regulator of immune activation. CTLA-4 haploinsufficiency is known to be associated with dysregulation of FOXP3+ regulatory T cells, hyperactiv...
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Article
A digest of the Evidence-Based Clinical Practice Guideline for Nephrotic Syndrome 2020
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Article
Open AccessNephrotic syndrome due to preeclampsia before 20 weeks of gestation: a case report
Preeclampsia (PE) refers to the development of hypertension and new-onset proteinuria or progressive organ damage (especially kidney) in a previously normotensive pregnant women after 20 weeks of gestation. Th...
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Article
Open AccessMembranous nephropathy associated with thrombospondin type-1 domain-containing 7A (THSD7A) in an adult woman with eosinophilia
A 30-year-old woman on steroid therapy for eosinophilia presented with nephrotic syndrome during steroid tapering. She was diagnosed with membranous nephropathy (MN) stage II–III (positive for IgG1 and IgG4) b...
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Chapter
The Bank of Japan’s Exchange-Traded Fund Purchases under Quantitative and Qualitative Easing with Yield Curve Control
This chapter highlights (ETF) purchases conducted by with . The policy to purchase stocks indirectly is unprecedented in terms of both scale and duration among major central banks. The purpose of this p...
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Article
Overview of the Bank of Japan’s unconventional monetary policy during the period 2013–2018
Unconventional monetary easing conducted by the Bank of Japan (BOJ) since 2013 has contributed to the yen’s depreciation, higher stock prices, and higher corporate profits. Meanwhile, the impacts on aggregate ...
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Article
Open AccessA grading system that predicts the risk of dialysis induction in IgA nephropathy patients based on the combination of the clinical and histological severity
Histological classification is essential in the clinical management of immunoglobulin A nephropathy (IgAN). However, there are limitations in predicting the prognosis of IgAN based on histological information ...
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Article
Combined cyclosporine and prednisolone therapy using cyclosporine blood concentration monitoring for adult patients with new-onset minimal change nephrotic syndrome: a single-center pilot randomized trial
Minimal change nephrotic syndrome (MCNS) responds well to steroids, but some patients show frequent relapses. Long-term steroid administration leads to various adverse effects. We previously reported the effec...
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Article
Open AccessLack of partial renal response by 12 weeks after induction therapy predicts poor renal response and systemic damage accrual in lupus nephritis class III or IV
Lupus nephritis class III or IV is associated with a poor prognosis for both patient and renal survival. Recommendations for the management of lupus nephritis have recently been established, and changing thera...
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Article
Open AccessRisk factors for allergic reaction at initial therapeutic plasma exchange in a single-center study: beware of high rates of severe allergic reaction
Therapeutic plasma exchange (TPE) is an important treatment modality for various diseases, but its use can be restricted by allergic reactions (AR). The aim of our study was to elucidate the frequency of and r...
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Article
Retroperitoneal hemorrhage caused by inferior epigastric artery injury
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Article
Overestimation of the risk of progression to end-stage renal disease in the poor prognosis’ group according to the 2002 Japanese histological classification for immunoglobulin A nephropathy
The current (2012) histological classification of immunoglobulin A nephropathy was established using a case–control study of 287 patients. However, the risk of progression to end-stage renal disease (ESRD) has...
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Article
Japan’s monetary policy in a challenging environment
The Bank of Japan (BOJ) is attempting to overcome the mild deflation that has lasted in Japan for nearly 15 years and to achieve its 2 % price stability target. In the face of the zero lower bound on short-ter...
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Article
Preprandial microemulsion cyclosporine administration is effective for patients with refractory nephrotic syndrome
The present study evaluated the clinical efficacy and pharmacokinetics of microemulsion cyclosporine A (ME-CyA) with modification from postprandial to preprandial administration in adult patients with refracto...
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Article
Imbalance between production and scavenging of hydroxyl radicals in patients maintained on hemodialysis
Reactive oxygen species are as being related to the pathophysiology of endstage renal disease (ESRD). We measured the plasma hydroxyl radical (·OH)-producing ability and ·OH-scavenging activity in patients wit...
