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  1. Article

    Open Access

    Glycine, the smallest amino acid, confers neuroprotection against d-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain

    Glycine is the smallest nonessential amino acid and has previously unrecognized neurotherapeutic effects. In this study, we examined the mechanism underlying the neuroprotective effect of glycine (Gly) against...

    Rahat Ullah, Myeung Hoon Jo, Muhammad Riaz… in Journal of Neuroinflammation (2020)

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    Article

    Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

    Cognitive decline and memory impairment induced by oxidative brain damage are the critical pathological hallmarks of Alzheimer’s disease (AD). Based on the potential neuroprotective effects of melatonin, we he...

    Tahir Muhammad, Tahir Ali, Muhammad Ikram… in Journal of Neuroimmune Pharmacology (2019)

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    Article

    Ferulic Acid Rescues LPS-Induced Neurotoxicity via Modulation of the TLR4 Receptor in the Mouse Hippocampus

    Microglia play a crucial role in the inflammatory brain response to infection. However, overactivation of microglia is neurotoxic. Toll-like receptor 4 (TLR4) is involved in microglial activation via lipopolys...

    Shafiq Ur Rehman, Tahir Ali, Sayed Ibrar Alam, Rahat Ullah… in Molecular Neurobiology (2019)