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  1. No Access

    Article

    Reuse of treated urban wastewater on the growth and physiology of Medicago sativa L. cv. Gea and Petroselinum crispum L. cv. Commun: correlation with oxydative stress and DNA damage

    The freshwater scarcity is one of the major environmental problems, which is why the water reuse has become a possible remedy to cope with the shortage of water needed for agriculture irrigation. This study fo...

    Imene Fekih, Sana Hamila, Sarra Bchir… in Environmental Science and Pollution Resear… (2023)

  2. No Access

    Article

    Prostaglandin Endoperoxide H Synthase-2 (PGHS-2) Variants and Risk of Obesity and Microvascular Dysfunction Among Tunisians: Relevance of rs5277 (306G/C) and rs5275 (8473T/C) Genetic Markers

    The purpose of this study was to determine the impact of six PGHS-2 genetic variants on obesity development and microvascular dysfunction. The study included 305 Tunisian subjects (186 normal weights, 35 overw...

    Ahlem Touir, Soumaya Boumiza, Hela ben Nasr, Sarra Bchir… in Biochemical Genetics (2021)

  3. No Access

    Article

    Impact of cathepsin D activity and C224T polymorphism (rs17571) on chronic obstructive pulmonary disease: correlations with oxidative and inflammatory markers

    Cathepsin D (CTSD) is an aspartyl proteinase that plays an important role in protein degradation, antigen processing and apoptosis. It has been associated with several pathologies such as cancer, Alzheimer’s d...

    Sarra Bchir, Soumaya Boumiza, Hela ben Nasr… in Clinical and Experimental Medicine (2021)

  4. No Access

    Article

    Alterations in acetylcholinesterase and butyrylcholinesterase activities in chronic obstructive pulmonary disease: relationships with oxidative and inflammatory markers

    This work focused on finding a relationship between acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities and the development and severity of COPD. The possible link of these enzymes to oxida...

    Amel Ben Anes, Hela Ben Nasr, Abdelhamid Garrouch… in Molecular and Cellular Biochemistry (2018)

  5. No Access

    Article

    MMP-2 (-1306 C/T) Polymorphism Affects Serum Matrix Metalloproteinase (MMP)-2 Levels and Correlates with Chronic Obstructive Pulmonary Disease Severity: A Case–Control Study of MMP-1 and -2 in a Tunisian Population

    The aim of this study was to determine the role of MMP-1 (-1607 1G/2G; -519 A/G) and MMP-2 (-1306 C/T; -735 C/T) polymorphisms in the development and severity of chronic obstructive pulmonary disease (COPD) in Tu...

    Sarra Bchir, Hela ben Nasr, Amel ben Anes… in Molecular Diagnosis & Therapy (2016)

  6. No Access

    Article

    Matrix Metalloproteinase-9 (279R/Q) Polymorphism is Associated with Clinical Severity and Airflow Limitation in Tunisian Patients with Chronic Obstructive Pulmonary Disease

    The aim of this study was to investigate the role of matrix metalloproteinase-9 (MMP-9) C-1562T and 279R/Q (836G>A) polymorphisms in the development of chronic obstructive pulmonary disease (COPD) in Tunisians an...

    Sarra Bchir, Hela ben Nasr, Imen Rekik Hakim… in Molecular Diagnosis & Therapy (2015)

  7. No Access

    Article

    Increased Oxidative Stress and Altered Levels of Nitric Oxide and Peroxynitrite in Tunisian Patients with Chronic Obstructive Pulmonary Disease: Correlation with Disease Severity and Airflow Obstruction

    This study was aimed to evaluate the oxidant–antioxidant imbalance in the pathogenesis of chronic obstructive pulmonary disease (COPD) in Tunisians. We assessed 16 parameters related to the oxidative status th...

    Amel ben Anes, Hamadi Fetoui, Sarra Bchir… in Biological Trace Element Research (2014)