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Article
Clinicopathologic and molecular features of sporadic microsatellite- and chromosomal-stable colorectal cancers
Chromosomal instability (CIN) and microsatellite instability (MSI) are two major causes of colorectal cancers. Recently, a percentage of colorectal cancers were found to be neither CIN nor MSI. This study was ...
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Article
A Simple Scoring System Based on Clinical Features to Predict Locally Advanced Rectal Cancers
The purpose of this study was to identify clinical risk factors and establish a prediction scoring system for locally advanced rectal cancer.
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Article
A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk
Studies on polymorphism of X-ray repair cross-complementing group 1 (XRCC1), group 3 (XRCC3), and colorectal cancer risk are inconclusive. The purpose of this study is to evaluate the role of XRCC1 R399Q, R194W, ...
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Article
Integration of genetic signature and TNM staging system for predicting the relapse of locally advanced colorectal cancer
To identify potential genetic markers in treated stage II–III colorectal cancer patients and predict 3-year tumor relapse using statistical models based on important clinical factors and significant genetic ma...
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Article
Analysis of Factors Associated with Prognosis After Colorectal Cancer Resection in 174 Chinese Elderly Patients
The purpose of the present study was to investigate risk factors associated with prognosis in elderly patients with colorectal cancer (CRC) and to determine treatment and follow-up strategies.
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Article
Unfavorable effect of small tumor size on cause-specific survival in stage IIA colon cancer, a SEER-based study
We sought to determine the prognostic role of tumor size on cause-specific survival (CSS) of patients with stage IIA colon cancer.
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Article
Open AccessSpecific microRNAs as novel biomarkers for combination chemotherapy resistance detection of colon adenocarcinoma
Colon cancer is a frequently occurring primary malignant tumor. Chemotherapy can reduce the risk of local and distant relapse. Therefore, it is very important to find new biomarkers that can predict chemoresis...
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Article
Real-world study of a novel prognostic scoring system: for a more precise prognostication and better clinical treatment guidance in stages II and III colon cancer
This study aimed to improve the American Joint Committee on Cancer (AJCC) Tumor Node Metastases (TNM) staging system and demonstrate the improvement in prognostic accuracy and clinical management guidance in c...
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Article
The effect of marital status by age on patients with colorectal cancer over the past decades: a SEER-based analysis
Marital status has been found as an independent prognostic factor for survival in colorectal cancer (CRC). However, it is unclear whether patients with different marital status have benefited the same from the...
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Article
Prognostic value of distant metastasis sites and surgery in stage IV colorectal cancer: a population-based study
We investigated the prognostic value of distant metastasis sites among patients with metastatic colorectal cancer (CRC) and the significance of metastasectomy and resection of the primary CRC.
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Article
Open AccessLaparoscopic surgery may decrease the risk of clinical anastomotic leakage and a nomogram to predict anastomotic leakage after anterior resection for rectal cancer
Anastomotic leakage is still one of the most dreaded complications after anterior resection for rectal cancer. This study aimed to identify risk factors for anastomotic leakage and to create a nomogram for pre...
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Article
Open AccessHER2 status is positively associated with vessel invasion of colorectal cancer: a retrospective large cohort study
HER2-positive colorectal cancer was drawn increasing attention in recent years. Accumulating evidence showed HER2-positive metastatic colorectal cancer could benefit from HER2-targeted therapy. While HER2 expr...
