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Design, synthesis and biological evaluation of some novel benzylidene-2-(4-phenylthiazol-2-yl) hydrazines as potential anti-inflammatory agents
A series of substituted benzylidene-2-(4-phenylthiazol-2-yl) hydrazines (2a–q) have been synthesized, characterized and evaluated for their anti-inflammatory activity by carrageenin-induced hind paw edema (acute ...
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Article
Molecular modeling studies of some thiazolidine-2,4-dione derivatives as 15-PGDH inhibitors
The quantitative structure–activity relationship (QSAR) studies were performed on a series of 34 thiazolidine-2,4-dione derivatives to find the structural features necessary for the inhibition of 15-PGDH. The ...