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  1. Article

    Open Access

    Comparison of Four Protocols for In Vitro Differentiation of Human Embryonic Stem Cells into Trophoblast Lineages by BMP4 and Dual Inhibition of Activin/Nodal and FGF2 Signaling

    Human embryonic stem cells (hESCs) cultured in media containing bone morphogenic protein 4 (BMP4; B) differentiate into trophoblast-like cells. Supplementing media with inhibitors of activin/nodal signaling (A...

    Zahra Anvar, Imen Chakchouk, Momal Sharif, Sangeetha Mahadevan… in Reproductive Sciences (2024)

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    Article

    Loss of the Maternal Effect Gene Nlrp2 Alters the Transcriptome of Ovulated Mouse Oocytes and Impacts Expression of Histone Demethylase KDM1B

    The subcortical maternal complex (SCMC) is a multiprotein complex in oocytes and preimplantation embryos that is encoded by maternal effect genes. The SCMC is essential for zygote-to-embryo transition, early e...

    Zahra Anvar, Imen Chakchouk, Momal Sharif, Sangeetha Mahadevan… in Reproductive Sciences (2023)