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Open AccessSuppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma
The resistance of lung cancer to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is one of the unconquered frontiers in chemotherapy. Mitogen-inducible gene 6 (Mig-6) is known to inhibit ...
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Open AccessDual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-derived reactive oxygen species (ROS) not only can promote cancer progression, but also they have recently emerged as mediators of the mucosal immune...
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Open AccessClinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma
Protein kinase C iota (PKCι) and protein kinase C zeta (PKCζ) are two atypical protein kinase (aPKC) enzymes that contribute to cell proliferation and cancer development. The Hippo/YAP pathway is commonly disr...
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Open AccessSpatially and spectrally resolved orbital angular momentum interactions in plasmonic vortex generators
Understanding the near-field electromagnetic interactions that produce optical orbital angular momentum (OAM) is crucial for integrating twisted light into nanotechnology. Here, we examine the cathodoluminesce...
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Open AccessIntegrative analysis of KIF4A, 9, 18A, and 23 and their clinical significance in low-grade glioma and glioblastoma
To determine the prognostic significance of kinesin superfamily gene (KIF) expression in patients with brain cancer, including low-grade glioma (LGG) and glioblastoma (GBM), we comprehensively analyzed KIFs in...
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Clinical Significance of the Thioredoxin System and Thioredoxin-Domain-Containing Protein Family in Hepatocellular Carcinoma
Oxidative stress occurs due to the excessive generation of cellular reactive oxygen species and antioxidant system dysfunction. The thioredoxin (TXN) system and TXN-domain-containing protein (TXNDC) family for...
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Expression of NOX Family Genes and Their Clinical Significance in Colorectal Cancer
The NADPH oxidase (NOX) family is overexpressed in many cancers and is associated with cancer cell proliferation and metastasis; however, little is known about the role of the NOX family in colorectal cancer (...
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Open AccessGene expression of NOX family members and their clinical significance in hepatocellular carcinoma
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex-derived reactive oxygen species (ROS) promote chronic liver inflammation and remodeling that can drive hepatocellular carcinoma development. ...
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Chapter and Conference Paper
Flammability Test Plan for Fire Safety of KSLV-II
The flammability of materials is regarded as a critical design factor in the aerospace industry. Employing flammable materials, however, is inevitable sometimes in develo** a launch vehicle. There are severa...
