-
Article
Open AccessHigher exposure to 1,3-butadiene is associated with more severe hearing loss
While volatile organic compounds (VOCs) impair various organs, their influence on hearing loss (HL) has not been extensively researched. We aimed to identify the association between VOCs and HL or high-frequen...
-
Article
Open AccessInsufficient nutrient intake in individuals with disabling hearing loss and the restoration of nutritional sufficiency in hearing aid users
Hearing loss affects some nutrient intake. Disabling hearing loss may exacerbate these issues. We aimed to evaluate nutrient intake and assess deficiencies based on functional hearing status. The study include...
-
Article
Inkjet printing MoS2 nanosheets for hydrogen sensing applications
2D nanomaterials are of great interest in many modern applications. In particular, MoS2 nanomaterial with a narrow band gap of 1.8 eV is expected as one of the best candidates for low-cost gas sensors. To reduce ...
-
Article
Open AccessNovel autosomal dominant TMC1 variants linked to hearing loss: insight into protein-lipid interactions
TMC1, which encodes transmembrane channel-like protein 1, forms the mechanoelectrical transduction (MET) channel in auditory hair cells, necessary for auditory function. TMC1 variants are known to cause autosomal...
-
Article
Open AccessAllelic hierarchy for USH2A influences auditory and visual phenotypes in South Korean patients
When medical genetic syndromes are influenced by allelic hierarchies, mutant alleles have distinct effects on clinical phenotypes. Genotype–phenotype correlations for Usher syndrome type 2 (USH2) suggest that ...
-
Article
Open AccessRamifications of POU4F3 variants associated with autosomal dominant hearing loss in various molecular aspects
POU4F3, a member of the POU family of transcription factors, commonly causes autosomal dominant deafness. Exome sequencing was used to identify four novel variants in POU4F3 (NM_002700.2), including c.564dupA: p....
-
Article
Open AccessPhenotypic and molecular basis of SIX1 variants linked to non-syndromic deafness and atypical branchio-otic syndrome in South Korea
Branchio-oto-renal (BOR)/branchio-otic (BO) syndrome is a rare disorder and exhibits clinically heterogenous phenotypes, marked by abnormalities in the ear, branchial arch, and renal system. Sporadic cases of ...
-
Article
3D Sacrificial Microchannels by Scaffold Removal Process for Electrical Characterization of Electrolytes
3D printing technology is promising for the fabrications of microfluidic devices. For both research and educational purposes, the efficient generations of highly organized microchannels are on demand. Here, we...
-
Article
Open AccessWFS1 autosomal dominant variants linked with hearing loss: update on structural analysis and cochlear implant outcome
Wolfram syndrome type 1 gene (WFS1), which encodes a transmembrane structural protein (wolframin), is essential for several biological processes, including proper inner ear function. Unlike the recessively inheri...
-
Chapter
Sensors and Instrumentation in Management and Online Control
The emission of greenhouse gases (GHGs) has become a social and urgent issue because it directly causes global warming, leading to various environmental problems. Among the different sectors of the agricultura...
-
Article
Tight modiolar proximity and feasibility of slim modiolar cochlear implant electrode array insertion in diverse etiologies of hearing loss
To report on our experience with the slim modiolar electrode (SME) especially focusing on the wide range of etiologies including inner ear anomalies, tumors, ossifications, and even revision surgeries.
-
Article
Open AccessFull etiologic spectrum of pediatric severe to profound hearing loss of consecutive 119 cases
Determining the etiology of severe-to-profound sensorineural hearing loss (SP-SNHL) in pediatric subjects is particularly important in aiding the decision for auditory rehabilitation. We aimed to update the et...
-
Article
Update on CD164 and LMX1A genes to strengthen their causative role in autosomal dominant hearing loss
Novel hearing loss (HL) genes are constantly being discovered, and evidence from independent studies is essential to strengthen their position as causes of hereditary HL. To address this issue, we searched our...
-
Article
Open AccessQuantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
Surgical plugging to treat superior semicircular canal dehiscence (SCD) has been proven to impede the effect of the third mobile window, abating cochleovestibular symptoms. Knowledge of superior semicircular c...
-
Article
Open AccessEffects of in vivo repositioning of slim modiolar electrodes on electrical thresholds and speech perception
The slim modiolar electrode has been reported to ensure better modiolar proximity than previous conventional perimodiolar electrodes and consistently high scala tympani localization. Nonetheless, variability i...
-
Article
Open AccessNovel KCNQ4 variants in different functional domains confer genotype- and mechanism-based therapeutics in patients with nonsyndromic hearing loss
Loss-of-function variant in the gene encoding the KCNQ4 potassium channel causes autosomal dominant nonsyndromic hearing loss (DFNA2), and no effective pharmacotherapeutics have been developed to reverse chann...
-
Article
Open AccessContralateral spreading of substances following intratympanic nanoparticle-conjugated gentamicin injection in a rat model
This study was performed to investigate the Eustachian tube as a potential route for contralateral spreading following intratympanic nanoparticle (NP)-conjugated gentamicin injection in a rat model. Sprague–Da...
-
Article
Open AccessLongitudinal analysis of surgical outcome in subjects with pulsatile tinnitus originating from the sigmoid sinus
A dominant sigmoid sinus with either diverticulum or dehiscence (SS-Div/SS-Deh) is a common cause of pulsatile tinnitus (PT). For PT originating from SS-Div/SS-Deh, an etiology-specific and secure reconstructi...
-
Article
Open AccessSimpler and effective radiological evaluations for modiolar proximity of a slim modiolar cochlear implant electrode
A new slim modiolar electrode (CI532/632) has been reported to ensure better modiolar proximity than conventional electrodes. Better modiolar proximity has been proposed to yield better electrode discriminatio...
-
Article
Open AccessRe-emergence of the Glossy Ibis (Plegadis falcinellus) in inland South Korea
Glossy Ibis (Plegadis falcinellus), which has never been recorded in South Korea, appeared on Jeju Island in 2018 and re-emerged in the inland area of Seocheon-gun (South Chungcheong Province) and in Goyang-si (G...
