5 Result(s)

Article

Crizotinib attenuates cancer metastasis by inhibiting TGFβ signaling in non-small cell lung cancer cells

Crizotinib is a clinically approved tyrosine kinase inhibitor for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring EML4-ALK fusion. Crizotinib was orig...

Soonbum Park, Eun A Cho, Jung Nyeo Chun, Da Young Lee… in Experimental & Molecular Medicine (2022)

Article

The effect of a newly developed mini-light-emitting diode catheter for interstitial photodynamic therapy in pancreatic cancer xenografts

So-Young Kim, Eun A. Cho, Sang Mun Bae, Sang-Yeob Kim… in Journal of Translational Medicine (2021)

Article

Designed ferritin nanocages displaying trimeric TRAIL and tumor-targeting peptides confer superior anti-tumor efficacy

TRAIL is considered a promising target for cancer therapy because it mediates activation of the extrinsic apoptosis pathway in a tumor-specific manner by binding to and trimerizing its functional receptors, DR...

Jae Do Yoo, Sang Mun Bae, Junyoung Seo, In Seon Jeon… in Scientific Reports (2020)

Article

Endoscopic Transplantation of Mesenchymal Stem Cell Sheets in Experimental Colitis in Rats

Owing to the recent progress in regenerative medicine technology, clinical trials that harnessed the regeneration and immune modulation potentiality of stem cells for treating IBD have shown promising results....

Sehyung Pak, Sung Wook Hwang, In Kyong Shim, Sang Mun Bae… in Scientific Reports (2018)

Article

Sulfasalazine attenuates evading anticancer response of CD133-positive hepatocellular carcinoma cells

CD133-positive cells in hepatocellular carcinoma (HCC) exhibit cancer stem cell (CSC)-like properties as well as resistance to chemotherapeutic agents and ionizing radiation; however, their function remains un...

Yeonhwa Song, Jaewoo Jang, Tae-Hoon Shin… in Journal of Experimental & Clinical Cancer … (2017)