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    Chapter

    The receptor binding domain of apolipoprotein E, linked to a model class A amphipathic helix, enhances internalization and degradation of LDL in fibroblasts

    Manjula Chaddha, Geeta Datta, David W. Garber in Peptides for the New Millennium (2002)

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    Chapter

    Atherogenicity of Triglyceride-Rich Lipoproteins: Cellular Aspects

    Abnormal triglyceride-rich lipoproteins (TGRLP) are found in many fasting hypertriglyceridemia (HTG) subjects and postprandially in subjects with profiles associated with cardiovascular risk (elevated plasma t...

    Francois M. Booyse, William A. Bradley in Drugs Affecting Lipid Metabolism (1993)

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    Chapter and Conference Paper

    A Cellular Basis for the Potential Atherogenicity of Triglyceride-Rich Lipoproteins

    Two potential intiating events in atherosclerosis are endothelial injury and the accumulation of lipid-filled foam cells in the arterial intima. Ross and Glomset suggested that atherosclerosis may be a respons...

    Sandra H. Gianturco, William A. Bradley in Pathobiology of the Human Atherosclerotic Plaque (1990)

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    Article

    Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100

    Apolipoprotein (apo) B-100, the major protein component in low density lipoprotein (LDL), is the ligand that binds to the LDL receptor1. It is important in the metabolism of LDL and elevated plasma levels of LDL-...

    Chao-Yuh Yang, San-Hwan Chen, Sandra H. Gianturco, William A. Bradley in Nature (1986)

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    Article

    Abnormal suppression of 3-hydroxy-3-methylglutaryl-CoA reductase activity in cultured human fibroblasts by hypertriglyceridemic very low density lipoprotein subclasses

    Our previous studies showed that hypertriglyceridemic very low density lipoproteins (HTG VLDL) are functionally abnormal. HTG VLDL, but not normal VLDL, suppress HMG-CoA reductase in cultured normal human fibr...

    Sandra H. Gianturco, Christopher J. Packard, James Shepherd, Louis C. Smith in Lipids (1980)