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  1. Article

    Open Access

    Placebo effects in randomized trials of pharmacological and neurostimulation interventions for mental disorders: An umbrella review

    There is a growing literature exploring the placebo response within specific mental disorders, but no overarching quantitative synthesis of this research has analyzed evidence across mental disorders. We carri...

    Nathan T. M. Huneke, Jay Amin, David S. Baldwin, Alessio Bellato in Molecular Psychiatry (2024)

  2. Article

    Open Access

    Clarifying and extending our understanding of problematic pornography use through descriptions of the lived experience

    Problematic pornography use (PPU) is a complex and growing area of research. However, knowledge of the PPU lived experience is limited. To address this gap, we conducted an online qualitative study with 67 ind...

    Campbell Ince, Leonardo F. Fontenelle, Adrian Carter, Lucy Albertella in Scientific Reports (2023)

  3. No Access

    Article

    Hazardous Alcohol Use in Trichotillomania

    Trichotillomania is a prevalent mental health condition characterized by repetitive hair-pulling. Its relationship to alcohol use problems has received virtually no research scrutiny. Adults with trichotilloma...

    Jon E. Grant, Madison Collins, Eve Chesivoir in Psychiatric Quarterly (2023)

  4. Article

    Open Access

    The impact of the initial COVID-19 outbreak on young adults’ mental health: a longitudinal study of risk and resilience factors

    Few studies assessing the effects of COVID-19 on mental health include prospective markers of risk and resilience necessary to understand and mitigate the combined impacts of the pandemic, lockdowns, and other so...

    Anna Wiedemann, Jan Stochl, Sharon A. S. Neufeld, Jessica Fritz in Scientific Reports (2022)

  5. No Access

    Article

    Cortical dopamine reduces the impact of motivational biases governing automated behaviour

    Motivations shape our behaviour: the promise of reward invigorates, while in the face of punishment, we hold back. Abnormalities of motivational processing are implicated in clinical disorders characterised by...

    Vanessa Scholz, Roxanne W. Hook, Mojtaba Rostami Kandroodi in Neuropsychopharmacology (2022)

  6. No Access

    Article

    Reward processing in trichotillomania and skin picking disorder

    Trichotillomania (hair pulling disorder) and skin picking disorder are common and often debilitating mental health conditions, grouped under the umbrella term of body focused repetitive behaviors (BFRBs). Alth...

    Jon E. Grant, Tara S. Peris, Emily J. Ricketts in Brain Imaging and Behavior (2022)

  7. Article

    Open Access

    Structural gray matter differences in Problematic Usage of the Internet: a systematic review and meta-analysis

    Problematic Usage of the Internet (PUI) has been linked to diverse structural gray matter changes in individual data studies. However, no quantitative synthesis across studies has been conducted. We aimed to i...

    Jeremy E. Solly, Roxanne W. Hook, Jon E. Grant, Samuele Cortese in Molecular Psychiatry (2022)

  8. Article

    Open Access

    The effects of lisdexamfetamine dimesylate on eating behaviour and homeostatic, reward and cognitive processes in women with binge-eating symptoms: an experimental medicine study

    Lisdexamfetamine dimesylate (LDX) is the only drug currently approved by the FDA for the treatment of Binge-Eating Disorder (BED), but little is known about the behavioural mechanisms that underpin the efficac...

    Elizabeth Schneider, Elizabeth Martin, Pia Rotshtein in Translational Psychiatry (2022)

  9. Article

    Open Access

    Transdiagnostic phenotypes of compulsive behavior and associations with psychological, cognitive, and neurobiological affective processing

    Compulsivity is a poorly understood transdiagnostic construct thought to underlie multiple disorders, including obsessive-compulsive disorder, addictions, and binge eating. Our current understanding of the cau...

    Lauren Den Ouden, Chao Suo, Lucy Albertella in Translational Psychiatry (2022)

  10. Article

    Correction to: Monoamine Oxidase Inhibitors (MAOIs) in Psychiatric Practice: How to Use them Safely and Effectively

    Samuel R. Chamberlain, David S. Baldwin in CNS Drugs (2022)

  11. Article

    Authors’ Reply to Ulrich: Comment on ‘Monoamine Oxidase Inhibitors (MAOIs) in Psychiatric Practice: How to Use Them Safely and Effectively’

    David S. Baldwin, Samuel R. Chamberlain in CNS Drugs (2022)

  12. No Access

    Reference Work Entry In depth

    Obsessive Compulsive Disorders

    Obsessive-compulsive disorder (OCD) is a common and debilitating psychiatric condition. Relatively little, however, is understood about the etiology and brain basis of OCD despite decades of research. Although...

    Jon E. Grant, Samuel R. Chamberlain in Neuroscience in the 21st Century (2022)

  13. No Access

    Reference Work Entry In depth

    Linking Addictive and Obsessive-Compulsive Behaviors

    Addictive and obsessive-compulsive behaviors share a number of conceptual similarities and risk factors, indicating potential transdiagnostic mechanisms. This chapter reviews these similarities, with a focus o...

    Lucy Albertella, Samuel R. Chamberlain in Handbook of Substance Misuse and Addictions (2022)

  14. No Access

    Living Reference Work Entry In depth

    Linking addictive and obsessive-compulsive behaviours

    Addictive and obsessive-compulsive behaviors share a number of conceptual similarities and risk factors, indicating potential transdiagnostic mechanisms. This chapter reviews these similarities, with a focus o...

    Lucy Albertella, Samuel R. Chamberlain in Handbook of Substance Misuse and Addictions

  15. Article

    Open Access

    Author Correction: Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom

    Adam Hampshire, Peter J. Hellyer, Eyal Soreq, Mitul A. Mehta in Nature Communications (2021)

  16. Article

    Open Access

    Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom

    The COVID-19 pandemic (including lockdown) is likely to have had profound but diverse implications for mental health and well-being, yet little is known about individual experiences of the pandemic (positive a...

    Adam Hampshire, Peter J. Hellyer, Eyal Soreq, Mitul A. Mehta in Nature Communications (2021)

  17. Article

    Open Access

    Digital Hazards for Feeding and Eating: What We Know and What We Don't

    We aimed to accrue recent evidence exploring effects of modern online activities (e.g., Internet use) on feeding and eating disorder symptoms, and related traits. We examined available evidence to ascertain an...

    Konstantinos Ioannidis, Samuel R Chamberlain in Current Psychiatry Reports (2021)

  18. No Access

    Article

    Monoamine Oxidase Inhibitors (MAOIs) in Psychiatric Practice: How to Use them Safely and Effectively

    Monoamine oxidase inhibitors (MAOIs) were among the first licensed pharmacological treatments for patients with depression but over time have fallen out of mainstream clinical use. This has led to a loss of cl...

    Samuel R. Chamberlain, David S. Baldwin in CNS Drugs (2021)

  19. Article

    Open Access

    Personality traits and their clinical associations in trichotillomania and skin picking disorder

    Despite being discussed in the psychiatric literature for decades, very little is known about personality features associated with trichotillomania and skin picking disorder (known as body focused repetitive b...

    Jon E. Grant, Samuel R. Chamberlain in BMC Psychiatry (2021)

  20. Article

    Open Access

    Brain micro-architecture and disinhibition: a latent phenoty** study across 33 impulsive and compulsive behaviours

    Impulsive and compulsive symptoms are common, tend to co-occur, and collectively account for a substantive global disease burden. Latent phenoty** offers a promising approach to elucidate common neural mecha...

    Rafa Romero-Garcia, Roxanne W. Hook, Jeggan Tiego in Neuropsychopharmacology (2021)

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