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  1. Article

    Fluorocarbon Emulsions as a Blood Substitute

    In 1966 CLARK discovered that animals breathing certain perfluorinated liquids can transfer enough oxygen and carbon dioxide to sustain life [Science 152: 1755, 1966]. This suggested that these liquids may serve ...

    Leland C Clark Jr., Samuel Kaplan, Fernando Becattini in Pediatric Research (1970)

  2. Article

    Echocardiography in the diagnosis of neonatal congenital heart disease

    Since its introduction in 1954, diagnostic ultrasound has been used to record the movement of atrio-ventricular valves, to measure atrial and ventricular dimensions, left venticular free wall thickness, left v...

    Richard A Meyer, Samuel Kaplan in Pediatric Research (1971)

  3. Article

    ECHOCARDIOGRAPHIC ASSESSMENT OF PATENT DUCTUS ARTERIOSOS IN PREMATURES WITH RESPIRATORY DISTRESS

    Non-invasive evaluation of significant left to right shunting through a patent ductus arteriosus (PDA) is difficult in premature infants with respiratory distress. Sixteen infants (gestation 26-36 weeks; weigh...

    Barry Baylen, Richard A Meyer, Samuel Kaplan in Pediatric Research (1974)

  4. Article

    NON-INVASIVE RIGHT AND LEFT SYSTOLIC TIME INTERVALS BY ECHOCARDIOGRAPHY

    Evaluation of left ventricular performance has been possible by the measurement of systolic time intervals (STI's). However non-invasive assessment of right ventricular performance has been difficult because i...

    Stephen Hirschfeld, Richard A Meyer, Samuel Kaplan in Pediatric Research (1974)

  5. Article

    NON-INVASIVE ESTIMATION OF LEFT TO RIGHT SHUNTS USING ECHOCARDIOGRAMS AND RADIONUCLIDE ANGIOCARDIOGRAPHY

    Echocardtography (echo) has been used in children with ventricular septal defects (VSD) to estimate the magnitude of left to right shunt (Qp/Qs) and has been correlated with Qp/Qs measured by Fick method using...

    Terrence Dillon, Michael J Gelfand, James Breitweser, Richard A Meyer in Pediatric Research (1977)

  6. Article

    SPECTRUM OF EXERCISE RESPONSES IN CHILDREN WITH AORTIC STENOSIS

    Significant abnormalities in cardiovascular dynamics may occur during exercise (Ex) in patients (P) with aortic stenosis (AS). This study was designed to record systolic pressure (ESP), electrocardiogram (ECG)...

    Frederick W James, Samuel Kaplan in Pediatric Research (1977)

  7. Article

    212 MYOCARDIAL PERFUSION DURING EXERCISE IN DOGS WITH LEFT VENTRICULAR OBSTRUCTION ABOVE AND BELOW CORONARY ARTERIES

    Strenuous exercise is thought to induce global myocardial ischemia in the presence of left ventricular hypertrophy (LVH) and normal coronary arteries. Myocardial perfusion (MBF) and cardiac index (CI) were mea...

    Jeffrey T Whitmer, Frederick W James, Samuel Kaplan in Pediatric Research (1981)

  8. Article

    183 “RESPIRATOR PARADOX” IN PREMATURE INFANTS WITH RESPIRATORY DISTRESS SYNDROME

    Eleven premature infants (28-32 wks gestation; 900-1400 grams) had echocardiograms performed during the first week of life. Left ventricular (LV) pre-ejection periods (PEP) and ejection times (ET) were measure...

    Mark D Reller, Uma R Kotagal, Richard A Meyer, Samuel Kaplan in Pediatric Research (1981)

  9. Article

    THE SPECTRUM OF PULMONARY VASCULAR DISEASE IN INFANTS AND CHILDREN WITH CARDIOMYOPATHY

    The presence of pulmonary vascular disease (PVD) in patients undergoing cardiac transplantation may result in death from acute right ventricular failure. This study was undertaken to explore the frequency and ...

    Anne M Murphy, David Witte, Kevin Bove, Samuel Kaplan in Pediatric Research (1987)

  10. Article

    NORMALIZATION OF PLASMA NOREPINEPHRINE FOLLOWING REPAIR OF INTRACARDIAC LEFT TO RIGHT SHUNTS

    Plasma norepinephrine (PNE) is elevated in patients with conogestive heart failure (CHF) and the degree of elevation corresponds to the severity of the CHF. This study was performed to determine whether PNE re...

    Robert D Ross, Stephen R Daniels, David C Schwartz, David Hannon in Pediatric Research (1987)

  11. Article

    CHARACTERIZATION OF THE QT INTERVAL DURING UPRIGHT EXERCISE IN CHILDREN

    The QTc interval which reflects ventricular activation/repolarization has not been characterized in children during exercise. We studied 60 children (ages 5-18 years) who underwent upright cycle ergometry accordi...

    Stephen Cyran, Wayne Mays, Frederick W James, Samuel Kaplan in Pediatric Research (1987)

  12. Article

    CHILDREN WITH COMPENSATED AORTIC STENOSIS MAINTAIN ENHANCED EJECTION PERFORMANCE DURING EXERCISE

    It has been shown that ejection phase indices are elevated in children with aortic stenosis (AS) at rest. We performed two-dimensional and M-mode echocardiography in 14 patients with AS and in 7 normal (NL) ch...

    R Dennis Steed, Richard M Martinez, Stephen R Daniels in Pediatric Research (1987)

  13. Article

    ABNORMALITIES IN VENTRICULAR ACTIVATION AND REPOLARIZATION IN SICKLE CELL DISEASE AND NORMAL SIBLINGS

    Prolongation of the QTc interval can result from lengthening of ventricular activation and/or repolarization due to ischemia. Although we have previously reported exercise induced ischemic-like ST depression in c...

    Stephen Cyran, Wayne Mays, Frederick W James, Samuel Kaplan in Pediatric Research (1987)