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Article
Open AccessClinical Meaningfulness of Response to Tanezumab in Patients with Chronic Low Back Pain: Analysis From a 56-Week, Randomized, Placebo- and Tramadol-Controlled, Phase 3 Trial
A recent phase 3, randomized, placebo- and tramadol-controlled trial (56-week treatment/24-week safety follow-up) demonstrated efficacy of tanezumab 10 mg in patients with chronic low back pain (CLBP) and a hi...
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Open AccessWhen to write a neurology case report
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Article
Open AccessDisulfiram neuropathy: two case reports
Neuropathy is a rare adverse side effect of disulfiram therapy and is under-recognized. There have been few case reports documenting this side effect.
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Article
Open AccessParaproteinemic neuropathy: a practical review
The term paraproteinemic neuropathy describes a heterogeneous set of neuropathies characterized by the presence of homogeneous immunoglobulin in the serum. An abnormal clonal proliferation of B-lymphocytes or ...
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Article
Open AccessMisdiagnosis of inclusion body myositis: two case reports and a retrospective chart review
Sporadic inclusion body myositis is the most common adult myopathy in persons aged 50 years and older. The clinical presentation includes a chronic, slowly progressive course with a predilection for weakness o...
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Open AccessChiari malformation type I with cervicothoracic syringomyelia masquerading as bibrachial amyotrophy: a case report
Clinical presentation of syringomyelia can mimic a variety of neuromuscular disorders. A misdiagnosis can result in progressive pressure on the spinal cord, causing the development of severe irreversible neuro...
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Open AccessMyasthenia gravis associated with invasive malignant thymoma: two case reports and a review of the literature
Approximately ten to fifteen percent of patients with myasthenia gravis are found to have a thymoma, and twenty to twenty-five percent of patients with thymoma have myasthenia gravis. Thymomatous myasthenia gr...
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Open AccessKennedy disease misdiagnosed as polymyositis: a case report
Polymyositis is an immune-mediated myopathy with clinical features of proximal muscle weakness. Dysphagia and neck flexor weakness can develop along with respiratory muscle weakness as the disease progresses. ...
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Open AccessCervicothoracic spinal cord and pontomedullary injury secondary to high-voltage electrocution: a case report
High-voltage electrical injuries are uncommonly reported and may predispose to both immediate and delayed neurologic complications.
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Article
Open AccessEmotional stress as a trigger of myasthenic crisis and concomitant takotsubo cardiomyopathy: a case report
Myasthenia gravis is a neuromuscular junction post-synaptic autoimmune disorder. Myasthenic crisis is characterized by respiratory failure requiring mechanical ventilation. Takotsubo cardiomyopathy is a rare c...
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Article
Open AccessAmyotrophic lateral sclerosis-motor neuron disease, monoclonal gammopathy, hyperparathyroidism, and B12 deficiency: case report and review of the literature
Amyotrophic lateral sclerosis (the most common form of motor neuron disease) is a progressive and devastating disease involving both lower and upper motor neurons, typically following a relentless path towards...