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Article
Accelerating healing of excisional wound with alginate hydrogel containing naringenin in rat model
Wounds have always been considered as one of the most common physical damages. Therefore, various researches have been conducted to find an appropriate method to improve wound healing process. Among various ma...
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Article
Open AccessA tailored polylactic acid/polycaprolactone biodegradable and bioactive 3D porous scaffold containing gelatin nanofibers and Taurine for bone regeneration
The focus of the current study was to develop a functional and bioactive scaffold through the combination of 3D polylactic acid (PLA)/polycaprolactone (PCL) with gelatin nanofibers (GNFs) and Taurine (Tau) for...
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Article
Electrospun Poly(ε-caprolactone)/Gelatin Nanofibrous Mat Containing Selenium as a Potential Wound Dressing Material: In Vitro and In Vivo Study
In the current study, selenium particles were loaded into poly(ε-caprolactone)/gelatin nanofibrous matrices in order to fabricate a potential wound dressing. The mats were produced by electrospinning of poly(ε...
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Article
Open AccessElectrospun cellulose acetate/gelatin nanofibrous wound dressing containing berberine for diabetic foot ulcer healing: in vitro and in vivo studies
Functional wound dressing with tailored physicochemical and biological properties is vital for diabetic foot ulcer (DFU) treatment. Our main objective in the current study was to fabricate Cellulose Acetate/Ge...
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Article
A promising wound dressing based on alginate hydrogels containing vitamin D3 cross-linked by calcium carbonate/d-glucono-δ-lactone
In the present study, we fabricated vitamin D3-loaded alginate hydrogel and assessed its wound healing capability in the animal model. The various concentrations of vitamin D3 were added to the pre-dissolved sodi...
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Article
Open AccessA novel polycaprolactone/carbon nanofiber composite as a conductive neural guidance channel: an in vitro and in vivo study
The current study aimed to investigate the potential of carbon nanofibers to promote peripheral nerve regeneration. The carbon nanofiber-imbedded scaffolds were produced from polycaprolactone and carbon nanofi...
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Article
Sciatic nerve regeneration by using collagen type I hydrogel containing naringin
In the present study, collagen hydrogel containing naringin was fabricated, characterized and used as the scaffold for peripheral nerve damage treatment. The collagen was dissolved in acetic acid, naringin add...
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Article
Polyurethane/Gelatin Nanofiber Neural Guidance Conduit in Combination with Resveratrol and Schwann Cells for Sciatic Nerve Regeneration in the Rat Model
Peripheral nerve injury is a serious challenge which influences 2.8 percent of trauma patients. Tissue engineering of peripheral nerves mainly focuses on axonal regeneration via various nerve guides. The aim o...
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Article
Unrestricted Somatic Stem Cells Loaded in Nanofibrous Conduit as Potential Candidate for Sciatic Nerve Regeneration
Motor and sensory recovery following critical size peripheral nerve defects is often incomplete. Although nerve grafting has been proposed as the gold standard, it is associated with several disadvantages. Her...
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Article
Promotion of excisional wound repair by a menstrual blood-derived stem cell-seeded decellularized human amniotic membrane
This is the first study demonstrating the efficacy of menstrual blood-derived stem cell (MenSC) transplantation via decellularized human amniotic membrane (DAM), for the promotion of skin excisional wound repa...
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Article
Regeneration of sciatic nerve crush injury by a hydroxyapatite nanoparticle-containing collagen type I hydrogel
The current study aimed to enhance the efficacy of peripheral nerve regeneration using a hydroxyapatite nanoparticle-containing collagen type I hydrogel. A solution of type I collagen, extracted from the rat t...
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Article
Polyurethane/Gelatin Nanofibrils Neural Guidance Conduit Containing Platelet-Rich Plasma and Melatonin for Transplantation of Schwann Cells
The current study aimed to enhance the efficacy of peripheral nerve regeneration using a biodegradable porous neural guidance conduit as a carrier to transplant allogeneic Schwann cells (SCs). The conduit was ...
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Article
Neural tissue regeneration by a gabapentin-loaded cellulose acetate/gelatin wet-electrospun scaffold
In the present study, gabapentin (GBP), an anticonvulsant drug used as an analgesic to control the neuropathic pains, was incorporated with cellulose acetate (CA) and gelatin (Gel) in order to develop a potent...
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Article
Naringin-loaded Poly(ε-caprolactone)/Gelatin Electrospun Mat as a Potential Wound Dressing: In vitro and In vivo Evaluation
In the present study, naringin, a flavonoid isolated from the grape and citrus fruit species, was incorporated with poly(ε-caprolactone)/gelatin composite mats in order to develop a potential wound dressing. T...
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Article
Sciatic nerve regeneration by transplantation of menstrual blood-derived stem cells
This is the first study demonstrating the efficacy of menstrual blood-derived stem cell (MenSC) transplantation via a neural guidance conduit, for peripheral nerve regeneration. The synthesized poly (ɛ-caprola...
