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  1. Article

    Long COVID and kidney disease

    Kidney involvement is common in patients with acute SARS-CoV-2 infection, and subclinical inflammation and injury may persist for many months, resulting in a progressive decline in kidney function that leads t...

    Sachin Yende, Chirag R. Parikh in Nature Reviews Nephrology (2021)

  2. Article

    Open Access

    Plasma lipid profiling for the prognosis of 90-day mortality, in-hospital mortality, ICU admission, and severity in bacterial community-acquired pneumonia (CAP)

    Pneumonia is the most common cause of mortality from infectious diseases, the second leading cause of nosocomial infection, and the leading cause of mortality among hospitalized adults. To improve clinical man...

    Mohammad M. Banoei, Hans J. Vogel, Aalim M. Weljie, Sachin Yende in Critical Care (2020)

  3. No Access

    Article

    Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

    Sepsis-associated immunosuppression increases hospital-acquired infection and viral reactivation risk. A key underlying mechanism is programmed cell death protein-1 (PD-1)-mediated T-cell function impairment. ...

    Richard S. Hotchkiss, Elizabeth Colston, Sachin Yende in Intensive Care Medicine (2019)

  4. Article

    Open Access

    Precision medicine for all? Challenges and opportunities for a precision medicine approach to critical illness

    All of medicine aspires to be precise, where a greater understanding of individual data will lead to personalized treatment and improved outcomes. Prompted by specific examples in oncology, the field of critic...

    Christopher W. Seymour, Hernando Gomez, Chung-Chou H. Chang in Critical Care (2017)

  5. Article

    Open Access

    Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia

    Metabolomics is a tool that has been used for the diagnosis and prognosis of specific diseases. The purpose of this study was to examine if metabolomics could be used as a potential diagnostic and prognostic t...

    Mohammad M. Banoei, Hans J. Vogel, Aalim M. Weljie, Anand Kumar in Critical Care (2017)

  6. Article

    Open Access

    Understanding the complex host response in sepsis: is diabetes the key?

    Florian B. Mayr, Sachin Yende in Critical Care (2016)

  7. Article

    Open Access

    Understanding skeletal muscle wasting in critically ill patients

    No abstract

    Frank Lodeserto, Sachin Yende in Critical Care (2014)

  8. Article

    Open Access

    Benefits of lung-protective ventilation: looking beyond the ICU

    No abstract.

    Namita Gupta, Sachin Yende in Critical Care (2014)

  9. Article

    Open Access

    Effects of intra-abdominal sepsis on atherosclerosis in mice

    Sepsis and other infections are associated with late cardiovascular events. Although persistent inflammation is implicated, a causal relationship has not been established. We tested whether sepsis causes vascu...

    Ata Murat Kaynar, Sachin Yende, Lin Zhu, Daniel R Frederick in Critical Care (2014)

  10. Article

    Blood transfusion for upper gastrointestinal bleeding: is less more again?

    The hemoglobin threshold for transfusion of red blood cells in patients withacute gastrointestinal (GI) bleeding is controversial. We compared theefficacy and safety of a restrictive transfusion strategy with ...

    Mohammed Al-Jaghbeer, Sachin Yende in Critical Care (2013)

  11. No Access

    Article

    Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study

    To determine the global metabolomic profile as measured in circulating plasma from surviving and non-surviving patients with community-acquired pneumonia (CAP) and sepsis.

    Christopher W. Seymour, Sachin Yende, Melanie J. Scott in Intensive Care Medicine (2013)

  12. Article

    A touch of cooling may help

    Schortgen F, Clabault K, Katsahian S, Devaquet J, Mercat A, Deye N, Dellamonica J, Bouadma L, Cook F, Beji O, Brun-Buisson C, Lemaire F, Brochard L: Multicenter randomized controlled clinical trial of fever contr...

    Akram M Zaaqoq, Sachin Yende in Critical Care (2013)

  13. Article

    Towards personalized medicine in sepsis: Quest for Shangri-La?

    Boomer JS, To K, Chang KC, Takasu O, Osborne DF, Walton AH, Bricker TL, Jarman SD 2nd, Kreisel D, Krupnick AS, Srivastava A, Swanson PE, Green JM, Hotchkiss RS: Immunosuppression in patients who die of sepsis and...

    Ayan Sen, Sachin Yende in Critical Care (2013)

  14. Article

    Weighing risks and benefits of stress ulcer prophylaxis in critically ill patients

    Marik PE, Tajender Vasu T, Hirani A, Pachinburavan M: Stress ulcer prophylaxis in the new millennium: a systematic review and meta-analysis. Critical Care Med 2010, 38:11.

    Trupesh Chanpura, Sachin Yende in Critical Care (2012)

  15. Article

    Protocol-directed care in the ICU: making a future generation of intensivists less knowledgeable?

    Prasad M, Holmboe ES, Lipner RS, Hess BJ, Christie JD, Bellamy SL, Rubenfeld GD, Kahn JM. Clinical Protocols and Trainee Knowledge About Mechanical Ventilation. JAMA. 2011; 306(9):935-941. PubMed PMID: 2190013...

    Erik Diringer, Sachin Yende in Critical Care (2012)

  16. Article

    Glucocorticoid therapy for trauma - ready for prime time?

    Venkata S Aleti, Sachin Yende in Critical Care (2012)

  17. Article

    Revisiting Mars and Venus: understanding gender differences in critical illness

    Understanding the nature and biological basis of gender-determined differences in risk of and outcome from infection might identify new therapeutic targets, allow more individualised treatment, and facilitate ...

    Michael C Reade, Sachin Yende, Derek C Angus in Critical Care (2011)

  18. Article

    Pushing the envelope to reduce sedation in critically ill patients

    Olufunmilayo Ogundele, Sachin Yende in Critical Care (2010)

  19. Article

    Comparing different thrombolytic dosing regimens for treatment of acute pulmonary embolism

    Ammar Ghanem, Sachin Yende in Critical Care (2010)

  20. Article

    Epinephrine: Is it really the black sheep of vasoactive agents?

    Ritwick Agrawal, Ali Al-Khafaji, Sachin Yende in Critical Care (2010)

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