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  1. No Access

    Protocol

    Polymer-Based Delivery of RNA-Based Therapeutics in Ovarian Cancer

    RNA interference (RNAi) is a naturally occurring, powerful mechanism for gene silencing, based on the cleavage of a given target mRNA. It relies on small interfering RNAs (siRNAs) in the cell. Being similar in...

    Ulrike Weirauch, Daniela Gutsch, Sabrina Höbel, Achim Aigner in Ovarian Cancer (2013)

  2. Article

    Open Access

    Anti-tumor effects of fibroblast growth factor-binding protein (FGF-BP) knockdown in colon carcinoma

    Fibroblast growth factors FGF-1 and FGF-2 are often upregulated in tumors, but tightly bound to heparan sulphate proteoglycans of the extracellular matrix (ECM). One mechanism of their bioactivation relies on ...

    Daniel Schulze, Philipp Plohmann, Sabrina Höbel, Achim Aigner in Molecular Cancer (2011)

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