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Sabino Liuni
Biomedicine
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Article
Open AccessTRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours
TRIM8 plays a key role in controlling the p53 molecular switch that sustains the transcriptional activation of cell cycle arrest genes and response to chemotherapeutic drugs. The mechanisms that regulate TRIM8...
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Article
Open AccessClusterin transcript variants expression in thyroid tumor: a potential marker of malignancy?
Clusterin (CLU) is a ubiquitous multifunctional factor involved in neoplastic transformation. The CLU transcript variants and protein forms play a crucial role in balancing cells proliferation and death.
