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Article
Open AccessFrequent MED12 mutations in phyllodes tumours of the breast
Phyllodes tumours are rare fibroepithelial tumours of the breast, that include benign, borderline, and malignant lesions. Although the molecular basis of phyllodes tumours largely remains unknown, a recent exo...
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Article
Open AccessActivating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum
Heterotopic gastric-type epithelium, including gastric foveolar metaplasia (GFM) and gastric heterotopia (GH), is a common finding in duodenal biopsy specimens; however, there is still controversy regarding th...
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Article
Usefulness of endotoxin activity assay for early diagnosis of sepsis
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Article
Open AccessFrequent GNAS mutations in low-grade appendiceal mucinous neoplasms
The molecular basis for the development of appendiceal mucinous tumours, which can be a cause of pseudomyxoma peritonei, remains largely unknown.
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Article
Open AccessUrinary podocalyxin is an early marker for podocyte injury in patients with diabetes: establishment of a highly sensitive ELISA to detect urinary podocalyxin
Nephropathy, a major complication of diabetes, is the leading cause of end-stage renal disease. Recent studies have demonstrated that podocyte injury is involved in the onset of and progression to renal insuff...
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Article
Open AccessTumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation
Tumour necrosis reflects the presence of hypoxia, which can be indicative of an aggressive tumour phenotype. The aim of this study was to investigate whether histological necrosis is a useful predictor of outc...
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Chapter and Conference Paper
Electrochemical In-Situ Micropatterning of Cells and Polymers
We report two novel techniques “Electrochemical Bio-Lithography” that enables in-situ cellular micropatterning, and “Ultra Anisotropic Electrodeposition” for making micropatterns of conducting polymers. The fo...
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Article
An effective method for improving hemostasis in aortic root replacement with a composite graft
Hemostasis during aortic root replacement with a composite graft, consisting of a separate Dacron graft and a valve, was markedly improved by using a supra-annular aortic wall reinforcing suture (SAWR). Betwee...
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Article
Halofuginone inhibits neointimal formation of cultured rat aorta in a concentration-dependent fashion in vitro
Halofuginone, an anticoccidial quinoazolinone, can specifically inhibit collagen type α1 (I) synthesis and gene expression, and also inhibits cultured smooth muscle cell proliferation. The aim of this study wa...
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Chapter
Improved Performance Powder Metallurgy and In Situ Processed Multifilamentary Superconductors
The powder metallurgy (P/M) process and the In Situ process are alternative technologies for producing fine fiber, multifilamentary, A15 superconductors with high overall critical current densities, Jc, at high f...
