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Article
Open AccessCorrection: Corrigendum: Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles
Scientific Reports 7: Article number: 43923; published online: 06 March 2017; updated: 15 June 2017. The original version of this Article contained a typographical error in the spelling of the author F. A. J. ...
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Article
Open AccessEffect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles
Stem cells possess significant age-dependent differences in their immune-response profile. These differences were analysed by Next-Generation Sequencing of six age groups from bone marrow mesenchymal stem cell...
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Article
Open AccessFNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle
Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum i...
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Article
Open AccessInfluence of age on rat bone-marrow mesenchymal stem cells potential
Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age. Six age groups from bone m...
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Article
Open AccessTesticular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty
The Lin28/let-7 system, which includes the RNA-binding proteins, Lin28a/Lin28b and let-7 miRNAs, has emerged as putative regulator of puberty and male gametogenesis; yet, its expression pattern and regulation ...
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Article
Actions of 17β-estradiol on carbohydrate metabolism in liver, gills, and brain of gilthead sea bream Sparus auratus during acclimation to different salinities
The influence of gonadal maturation on seawater adaptability at the metabolic level was assessed in the euryhaline teleost Sparus auratus by treatment of immature fish with 17ß-estradiol (E2) followed by acclimat...