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  1. Article

    Open Access

    Correction: Corrigendum: Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles

    Scientific Reports 7: Article number: 43923; published online: 06 March 2017; updated: 15 June 2017. The original version of this Article contained a typographical error in the spelling of the author F. A. J. ...

    J. Fafián-Labora, I. Lesende-Rodriguez, P. Fernández-Pernas in Scientific Reports (2017)

  2. Article

    Open Access

    Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles

    Stem cells possess significant age-dependent differences in their immune-response profile. These differences were analysed by Next-Generation Sequencing of six age groups from bone marrow mesenchymal stem cell...

    J. Fafián-Labora, I. Lesende-Rodriguez, P. Fernández-Pernas in Scientific Reports (2017)

  3. Article

    Open Access

    FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle

    Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum i...

    B. M. Varela-Rodríguez, L. Pena-Bello, P. Juiz-Valiña in Scientific Reports (2016)

  4. Article

    Open Access

    Influence of age on rat bone-marrow mesenchymal stem cells potential

    Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age. Six age groups from bone m...

    J. Fafián-Labora, P. Fernández-Pernas, I. Fuentes, J. De Toro in Scientific Reports (2015)

  5. Article

    Open Access

    Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty

    The Lin28/let-7 system, which includes the RNA-binding proteins, Lin28a/Lin28b and let-7 miRNAs, has emerged as putative regulator of puberty and male gametogenesis; yet, its expression pattern and regulation ...

    S. Sangiao-Alvarellos, M. Manfredi-Lozano, F. Ruiz-Pino, S. León in Scientific Reports (2015)

  6. No Access

    Article

    Actions of 17β-estradiol on carbohydrate metabolism in liver, gills, and brain of gilthead sea bream Sparus auratus during acclimation to different salinities

    The influence of gonadal maturation on seawater adaptability at the metabolic level was assessed in the euryhaline teleost Sparus auratus by treatment of immature fish with 17ß-estradiol (E2) followed by acclimat...

    S. Sangiao-Alvarellos, J. M. Guzmán, R. Láiz-Carrión, J. M. Míguez in Marine Biology (2005)