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    Chapter

    Helenalin: Mechanism of Toxic Action

    Several range plants, including Hymenoxys odorata (bitterweed) and Helenium microencephalum DC (smallhead sneezeweed) contain toxic principles believed to be the etiologic agents responsible for severe losses of ...

    J. Merrill, H. L. Kim, S. Safe in Biological Reactive Intermediates III (1986)

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    Chapter

    Further Characterization and Applications of the 4-Chlorobiphenyl Hydroxylase Assay

    Studies of the metabolism-mediated covalent binding of halobiphenyls to cellular macromolecules revealed that the in vitro metabolism of 4-chlorobiphenyl (4-CBP) by hepatic microsomes is greatly enhanced by in vi...

    A. Parkinson, L. W. Robertson, S. Safe in Biological Reactive Intermediates—II (1982)

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    Article

    Lipid and alkali extractable fatty acids fromMucor rouxii: Effect of thermal changes in growth environment and age of cells

    The lipid levels of the fungusMucor rouxii are affected markedly by both the growth temperature and the age of the cells. Both chloroform-methanol extractable (fraction I) and alkali extractable (fraction II) fat...

    S. Safe in Lipids (1974)

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    Article

    Identification of 4-chloro-4′-hydroxybiphenyl and 4,4′-dichloro-3-hydroxybiphenyl as metabolites of 4-chloro- and 4,4′-dichlorobiphenyl fed to rats

    Identifizierung und Strukturaufklärung zweier Metaboliten von 4-Chorbiphenyl und 4,4′-Dichlorbiphenyl mittels NMR-Spektroskopie.

    S. Safe, O. Hutzinger, D. Ecobichon in Experientia (1974)

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    Article

    Effect of oxygen levels on the fatty acids and lipids ofMucor rouxii

    The effect of aerobic and oxygen limiting (anaerobic) growth conditions upon the fatty acid and lipid composition ofMucor rouxii has been examined. The aerobic cells contained a range of fatty acids typical of ph...

    S. Safe, J. Duncan in Lipids (1974)

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    Chapter

    Ion Kinetic Energy Spectroscopy: A New Mass Spectrometric Method for the Unambiguous Identification of Isomeric Chlorophenols

    Ion kinetic energy (IKE) spectroscopy is a technique which records the ionic decompositions which occur in the first field-free region of the mass spectrometer prior to the electric sector1,2. These ions can be r...

    S. Safe, W. D. Jamieson, O. Hutzinger in Mass Spectrometry and NMR Spectroscopy in … (1974)

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    Article

    Lipid composition ofChaetomium cochliodes: Effect of media

    The fatty acid and lipid compositions ofChaetomium cochliodes grown on three different media are compared. Although the growth media effects dramatic changes in the antibiotic production, only minor alterations i...

    S. Safe, D. Brewer in Lipids (1973)

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    Article

    7-Methyl-7-hexadecenoic acid: Isolation from lipids of the ocean sunfishMola mola (Linnaeus) 1758

    A fatty acid amounting to several per cent of the acids in various samples of the liver oil of the ocean sunfishMola mola was isolated and characterized as 7-methyl-7-hexadecenoic acid. This acid and the previous...

    R. G. Ackman, L. Safe, S. N. Hooper, M. Paradis, S. Safe in Lipids (1973)