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Article
Synthesis and Antimicrobial Activity of Phthalide Derivatives of Cytisine, Anabasine, and Salsoline
Aminophthalide derivatives of cytisine, anabasine, and salsoline were obtained in high yields via condensation of the alkaloids with o-formylbenzoic acid. Their structures were proven using 1H and 13C NMR spectro...
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Article
Reaction of o-Formylbenzoic Acid with Hydrazides of (Iso)niconitic and Hydroxybenzoic Acids
The reaction of nicotinic and isonicotinic acid hydrazides with o-formyl benzoic acid in ethanol led to the formation of the corresponding hydrazones. It was found that o-formyl benzoic acid reacted in aldehyde f...
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Article
SYNTHESIS, SPATIAL STRUCTURE, AND NOOTROPIC ACTIVITY OF N-CYANOMETHYLANABASINE
N-cyanomethylanabasine is prepared with an yield of 70% by the interaction of the alkaloid anabasine with glyconitrile. It is shown that the highest yield of the product is achieved by conducting the reaction ...
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Article
SYNTHESIS AND CRYSTAL STRUCTURE OF N-ETHYL-N-CYTISINOCARBOTHIOAMIDE
Based on (–)-cytisine alkaloid and ethyl isothiocyanate, N-ethyl-N-cytisinocarbothioamide is synthesized and its structure is proved by 1H NMR spectroscopy and single crystal X-ray diffraction. The mesomeric effe...
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Article
SYNTHESIS, CRYSTAL STRUCTURE, AND CONFORMATION OF N-ISONICOTINOYLPHTHALIMIDE
The reaction of phthalic acid anhydride with isonicotinoylhydrazide is carried out under severe conditions with the formation of cyclic phthalic acid imide N-isonicotinoylphthalimide. The structure of the comp...
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Article
SYNTHESIS, CRYSTAL STRUCTURE, AND STABILITY OF N-LUPINYLPHTHALIMIDE CONFORMERS
As a result of studying the interaction of chlorolupinine with potassium phthalimide, the optimal synthesis conditions for N-lupinylphthalimide by the Gabriel method are identified. The crystal structure of N...
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Article
Antiradical and Antimicrobial Activity of Thiosemicarbaside and 1,2,4-Triazole Derivatives of Hydroxybenzoic Acid
The antimicrobial and antioxidant activity of synthesized biologically active compounds have been evaluated in comparison with the standard antioxidant, ascorbic acid. The antioxidant activity of the compounds...
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Article
Synthesis of New Chromene-Containing Pyrrolofullerenes
Three-component condensation of substituted 4-oxochromene-3-carbaldehydes with sarcosine and fullerene C60 afforded 2′-(4-oxochromen-3-yl)-1′-methyl-2′,5′-dihydro-1′H-pyrrolo[3′,4′:1,9](C60-Ih)[5,6]fullerenes. Th...
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Article
Synthesis, Structure, and Biological Activity of Cinnamoyl-Containing Cytisine and Anabasine Alkaloids Derivatives
The reactions of the cytisine and anabasine alkaloids with cinnamic acid chloride have been studied, and hydrazinolysis of the resulting N-cinnamoylcytisine and N-cinnamoylanabazine has been carried out. The reac...
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Article
Synthesis and Intramolecular Heterocyclization of Selected Isonicotinic Acid Thiocarbazides
The reaction of isonicotinic acid hydrazide with ethyl-, allyl-, and cinnamoyl isothiocyanates has afforded the corresponding alkylthiosemicarbazides and the products of their intramolecular heterocyclization,...
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Article
Synthesis, Structure, and Properties of New Lupinine O-Acyl Derivatives
Acylation of the alkaloid lupinine produced O-cinnamoyllupinine and O-lipoyllupinine. The structure of O-cinnamoyllupinine was established by an X-ray crystal structure analysis.
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Article
Influence of Preliminary Demineralization on the Alkylation of Brown Coal in a Microwave Field
The results of a study of the effect of preliminary demineralization in a microwave field on the interaction of brown coal with butanol in the presence of an acid catalyst are reported. The effectiveness of th...
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Article
Synthesis and biological activity of hydrazones of o- and p-hydroxybenzoic acids. Spatial structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide
A series of hydrazones based on hydrazides of o- and p-hydroxybenzoic acids have been prepared. N-(5-Bromo-2-hydroxybenzylidene)-4-hydroxybenzohydrazide has been studied by X-ray diffraction analysis; its molecul...
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Article
Synthesis, Structure, and Antioxidant Activity of (4S,5S)-2-(1′-Bromo-2′-Phenylvinyl)-3,4-Dimethyl-5-Phenyl-1,3-Oxazolidine
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Article
Synthesis of new hydrazones based on o- and p-hydroxybenzohydrazides
o- and p-Hydroxybenzohydrazides reacted with various unsaturated aromatic aldehydes to give the corresponding N′-(hydroxybenzoyl)hydrazones. Inhibitory activity of the obtained hy...
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Article
Crystal structure of 2-(2-morpholinoacetyl) hydrazinocarbothioamide
The crystal structure of 2-(2-morpholinoacetyl)hydrazinocarbothioamide is determined by single crystal X-ray diffraction.
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Article
Briquetting of coal siftings and slacks in the presence of humates
Experimental data obtained in the development of a technology for the production of fuel briquettes from coal siftings and slacks are presented. The effects of the moisture content and the granulometric compos...
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Article
Synthesis and Hypotensive Activity of Novel Styryl Derivatives Based on Ethyl-4-(4-Methoxyphenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
Three-component condensation of thiourea, ethyl acetoacetic ester, and anisaldehyde was performed to synthesize ethyl-4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate. This comp...
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Article
Synthesis and Molecular Structure of 2-(4-Pyridyl)-3,4-Dimethyl-5-Phenyl-1,3-Oxazolidine
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Article
Synthesis of Thiourea Derivatives of the Alkaloids Anabasine, Cytisine, and d-Pseudoephedrine. Crystal Structure of N-ethyl-N-Anabasinocarbothioamide
Ethylthiourea derivatives of the alkaloids anabasine, cytisine, and d-pseudoephedrine were synthesized using ethylisothiocyanate. Their structures were proven using PMR spectroscopy. The molecular structure of N-...
