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  1. Article

    Open Access

    Acquisition of meiotic DNA repair regulators maintain genome stability in glioblastoma

    Glioblastoma (GBM), the most prevalent type of primary intrinsic brain cancer in adults, remains universally fatal despite maximal therapy, including radiotherapy and chemotherapy. Cytotoxic therapy generates ...

    M Rivera, Q Wu, P Hamerlik, A B Hjelmeland, S Bao, J N Rich in Cell Death & Disease (2015)

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  2. No Access

    Article

    PML-mediated signaling and its role in cancer stem cells

    The promyelocytic leukemia (PML) protein, initially discovered as a part of the PML/retinoic acid receptor alpha fusion protein, has been found to be a critical player in oncogenesis and tumor progression. Mul...

    W Zhou, S Bao in Oncogene (2014)

  3. No Access

    Article

    Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases

    Secreted protein acidic and rich in cysteine (SPARC) is an extracellular glycoprotein expressed in several solid cancers, including malignant gliomas, upon adoption of metastatic or invasive behaviors. SPARC e...

    Q Shi, S Bao, L Song, Q Wu, D D Bigner, A B Hjelmeland, J N Rich in Oncogene (2007)