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  1. No Access

    Article

    Pharmacokinetics of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, in man

    Objective: This study investigated the pharmacokinetics of the catechol-O-methyltransferase (COMT) inhibitor entacapone by giving simultaneously stable non-radioactive isotope 13C-entacapone int...

    H. Heikkinen, M. Saraheimo, S. Antila… in European Journal of Clinical Pharmacology (2001)

  2. No Access

    Article

    Haemodynamic interactions of a new calcium sensitizing drug levosimendan and captopril

    Objective: Levosimendan in a new inodilator drug that sensitises troponin C in heart muscle cells to calcium, thus improving contractility. In previous studies, a single 2 mg intravenous dose of levosimendan inc...

    S. Antila, L. Lehtonen, E.-P. Sandell, J. Eha… in European Journal of Clinical Pharmacology (1996)