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Article
'VEEP' in children with Hodgkin's disease – a regimen to decrease late sequelae
In an attempt to decrease the risk of second malignancies and future infertility in children with Hodgkin's disease (HD) while retaining acceptable remission rates, an anthracycline based regimen containing no...
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Article
Outcome of children with resistant and relapsed Hodgkin's disease
During the period 1974-89, 169 children with Hodgkin's disease were treated in the Paediatric Oncology Units of the Royal Marsden and St Bartholomew's Hospitals. The overall actuarial survival for the whole gr...
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Chapter and Conference Paper
SESAM: A biometric person identification system using sensor fusion
In the present paper we describe the person authentification system SESAM. Person identification and verification still is a very difficult task. Using one biometric feature, i.e. the photograph or the sound o...
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Article
Early identification of patients at risk of death due to infections, hemorrhage, or graft failure after allogeneic bone marrow transplantation on the basis of the leukocyte counts
Allograft recipients are often unwell with significant organ dysfunction by the time delayed or failed engraftment is diagnosed. We attempted to identify factors associated with graft failure, or death due to ...
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Article
Outcome of acute leukemia relapsing after bone marrow transplantation: utility of second transplants and adoptive immunotherapy
We studied 231 acute leukemia patients relapsing after allogeneic (n = 114) or autologous (n = 117) BMT to assess the outcome of further therapy. In general, all patients in good condition were eligible for secon...
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Article
Cytomegaloviremia after autografting for leukemia: clinical significance and lack of effect on engraftment
One hundred and fourteen patients with leukemia (66 cytomegalovirus (CMV)-seropositive and 48 CMV-seronegative) were monitored for cytomegaloviremia by early antigen detection or conventional viral culture aft...
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Article
Melphalan/TBI is not more carcinogenic than cyclophosphamide/TBI for transplant conditioning: follow-up of 725 patients from a single centre over a period of 26 years
As there is concern regarding the high carcinogenic potential of melphalan (Mel), 725 patients with haematological malignancies who received allogeneic (n = 714) or syngeneic (n = 11) transplants over the last 26...
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Article
Response to Maldonado et al
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Article
Novel SNPs in the CD18 gene validate the association with MPO-ANCA + vasculitis
Wegener granulomatosis (WG), microscopic polyangiitis (MP), and Churg-Strauss syndrome (CSS) are characterized by the presence of anti-neutrophil cytoplasmic antibodies (ANCA). Anti-myeloperoxidase (MPO)-ANCA ...
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Article
Allogeneic transplantation from HLA-matched sibling or partially HLA-mismatched related donors for primary refractory acute leukemia
Allogeneic transplantation is successful in a minority of patients with primary refractory acute leukemia (PRAL). An HLA-matched sibling donor (MSD) is available only in 30–40% of the patients, whereas a parti...
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Article
Kontaktdermatitis auf Spinat, Rauke und Schnittlauch
Eine 54-jährige Patientin, die seit 30 Jahren im Gemüseanbau tätig war, stellte sich in unserer Klinik mit stark juckenden und schmerzhaften Hautveränderungen an beiden Händen vor. Klinisch fand sich ein hyper...
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Article
Haploidentical vs autologous hematopoietic stem cell transplantation in patients with acute leukemia beyond first remission
This is a retrospective comparison of partially mismatched related donor transplantation (PMRDT) and autotransplantation (ABMT) in advanced acute leukemia. Patients underwent T-cell-depleted PMRDT (n=164) or ABMT...
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Article
Thalidomide after allogeneic haematopoietic stem cell transplantation: activity in chronic but not in acute graft-versus-host disease
Thalidomide was used to treat acute (n=21) or chronic (n=59) graft-vs-host disease (GVHD) in 80 haematopoietic stem cell allograft recipients after failure to respond to the combination of cyclosporine and cortic...
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Article
Arzneimittelexanthem durch pegyliertes Interferon-α2b
Im Vergleich zu rekombinantem "Standard"-Interferon-α2b führt die Anwendung von pegyliertem Interferon-α2b zu einer signifikant erhöhten Ansprechrate in der Therapie der chronischen Hepatitis C. Häufige Nebenwirk...
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Article
Topische Behandlung des subakut-kutanen Lupus erythematodes mit Tacrolimus
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Article
Palmoplantare Erythrodysästhesie nach intravenöser Therapie mit Docetaxel
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Article
Aktuelle Aspekte der Therapie mit topischen Calcineurininhibitoren
Seit ihrer Zulassung haben sich topische Calcineurininhibitoren als sehr gut wirksame Medikamente in der Therapie des atopischen Ekzems erwiesen. Am 10.03.2005 hat die amerikanische Arzneimittelzulassungsbehör...
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Article
Induktion einer Sarkoidose unter Therapie mit pegyliertem Interferon-α2a
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Article
Pityrosporumfollikulitis (Malasseziafollikulitis)
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Article
Rowell-Syndrom