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    Article

    Early identification of patients at risk of death due to infections, hemorrhage, or graft failure after allogeneic bone marrow transplantation on the basis of the leukocyte counts

    Allograft recipients are often unwell with significant organ dysfunction by the time delayed or failed engraftment is diagnosed. We attempted to identify factors associated with graft failure, or death due to ...

    J Mehta, R Powles, S Singhal, C Horton, G Middleton, T Eisen in Bone Marrow Transplantation (1997)

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    Article

    Outcome of acute leukemia relapsing after bone marrow transplantation: utility of second transplants and adoptive immunotherapy

    We studied 231 acute leukemia patients relapsing after allogeneic (n = 114) or autologous (n = 117) BMT to assess the outcome of further therapy. In general, all patients in good condition were eligible for secon...

    J Mehta, R Powles, J Treleaven, C Horton, S Meller in Bone Marrow Transplantation (1997)

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    Article

    Melphalan/TBI is not more carcinogenic than cyclophosphamide/TBI for transplant conditioning: follow-up of 725 patients from a single centre over a period of 26 years

    As there is concern regarding the high carcinogenic potential of melphalan (Mel), 725 patients with haematological malignancies who received allogeneic (n = 714) or syngeneic (n = 11) transplants over the last 26...

    S Kulkarni, R Powles, J Treleaven, S Singhal, C Horton in Bone Marrow Transplantation (2000)

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    Article

    Response to Maldonado et al

    S Vaidya, A Atra, S Meller in Bone Marrow Transplantation (2000)

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    Article

    Allogeneic transplantation from HLA-matched sibling or partially HLA-mismatched related donors for primary refractory acute leukemia

    Allogeneic transplantation is successful in a minority of patients with primary refractory acute leukemia (PRAL). An HLA-matched sibling donor (MSD) is available only in 30–40% of the patients, whereas a parti...

    S Singhal, R Powles, PJ Henslee-Downey, KY Chiang in Bone Marrow Transplantation (2002)

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    Article

    Haploidentical vs autologous hematopoietic stem cell transplantation in patients with acute leukemia beyond first remission

    This is a retrospective comparison of partially mismatched related donor transplantation (PMRDT) and autotransplantation (ABMT) in advanced acute leukemia. Patients underwent T-cell-depleted PMRDT (n=164) or ABMT...

    S Singhal, P J Henslee-Downey, R Powles, K Y Chiang in Bone Marrow Transplantation (2003)

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    Article

    Thalidomide after allogeneic haematopoietic stem cell transplantation: activity in chronic but not in acute graft-versus-host disease

    Thalidomide was used to treat acute (n=21) or chronic (n=59) graft-vs-host disease (GVHD) in 80 haematopoietic stem cell allograft recipients after failure to respond to the combination of cyclosporine and cortic...

    S Kulkarni, R Powles, B Sirohi, J Treleaven, R Saso in Bone Marrow Transplantation (2003)

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    Article

    Differential chemokine expression in chronic GVHD of the conjunctiva

    In chronic GVHD after BMT, the conjunctiva represents a target organ. GVHD can lead to severe inflammation and dry-eye syndrome (sicca syndrome). The molecular mechanisms are largely unknown. We examined the e...

    H Westekemper, S Meller, S Citak, C Schulte, K-P Steuhl in Bone Marrow Transplantation (2010)