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    Article

    Pharmacologic reversal of epigenetic silencing of the anticancer protein BRM: a novel targeted treatment strategy

    Tumor suppressor genes and oncogenes are both commonly altered during carcinogenesis. For oncogenes and other genes that drive growth, targeting mutated or activated forms (such as the EGFR-Her2/Nneu pathway) ...

    S Gramling, C Rogers, G Liu, D Reisman in Oncogene (2011)

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    Article

    Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk

    SWI/SNF (SWItch/sucrose non-fermentable) complexes are ATP-dependent chromatin remodeling enzymes critically involved in the regulation of multiple functions, including gene expression, differentiation, develo...

    G Liu, S Gramling, D Munoz, D Cheng, A K Azad, M Mirshams, Z Chen, W Xu in Oncogene (2011)