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  1. Article

    Open Access

    EHMTI-0149. Low CSF hypocretin-1 levels are associated with cluster headache

    M Barloese, P Jennum, N Lund, S Knudsen, S Gammeltoft… in The Journal of Headache and Pain (2014)

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  2. Article

    Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: reduced insulin antibody titres and preserved beta cell function

    The insulin-dependent diabetes mellitus 2 gene (IDDM2) is a type 1 diabetes susceptibility locus contributed to by the variable number of tandem repeats (VNTR) upstream of the insulin gene (INS). We investigated ...

    L. B. Nielsen, H. B. Mortensen, F. Chiarelli, R. Holl, P. Swift… in Diabetologia (2006)

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  3. Article

    40th EASD Annual Meeting of the European Association for the Study of Diabetes

    M. Veitenhansl, K. Stegner, F.-X. Hierl, C. Dieterle, H. Feldmeier, B. Gutt… in Diabetologia (2004)

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  4. No Access

    Chapter and Conference Paper

    Insulin receptor tyrosine kinase and insulin action

    Regulation of cellular metabolism and growth by insulin is the result of a series of events initiated by the interaction of the hormone with its cell surface receptors. The insulin receptor structure has been ...

    E. Van Obberghen, S. Gammeltoft… in Cell to Cell Signals in Mammalian Developm… (1989)

  5. No Access

    Chapter and Conference Paper

    Insulin Receptor: Role of Receptor Tyrosine Kinase in Insulin Signalling and Action

    Regulation of cellular metabolism and growth by insulin is the result of a series of events initiated by the interaction of the hormone with its cell surface receptors. The insulin receptor structure has been ...

    E. Van Obberghen, S. Gammeltoft… in Diabetes Mellitus: Pathophysiology and The… (1989)

  6. No Access

    Chapter

    Insulin receptors: Structure and function

    More than fifty years after the discovery of insulin, its cellular mechanism of action still remains one of the major obstacles in cell biology. Recent progress in the molecular characterization of the insulin...

    E. Van Obberghen, S. Gammeltoft in Development of Hormone Receptors (1987)

  7. No Access

    Article

    Insulin receptors: Structure and function

    The recent characterization of the human insulin receptor structure and its intrinsic tyrosine kinase activity represent major advances in our understanding of the mechanism of insulin action. It is reasonable...

    E. Van Obberghen, S. Gammeltoft in Experientia (1986)

  8. Article

    Receptor binding and biological effect of insulin in human adipocytes

    The binding of125I-labelled insulin to human adipocytes was studied at 37° C. The precipitability of the125I-labelled insulin preparation (0.03 nmol/l) in trichloroacetic acid and the concentration of biologicall...

    O. Andersen, J. Gliemann, S. Gammeltoft in Diabetologia (1977)

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  9. No Access

    Article

    Receptor-binding region of insulin

    X-ray analysis, circular dichroism, receptor binding and biological potencies of chemically modified insulins suggest that the conformation of the insulin molecule is critical to the formation of both the zinc...

    R. A. Pullen, D. G. Lindsay, S. P. Wood, I. J. Tickle, T. L. Blundell, A. Wollmer… in Nature (1976)

  10. Article

    The biological activity and the binding affinity of modified insulins determined on isolated rat fat cells

    A number of modified insulins were assayed for biological activity (increase in synthesis of lipids from glucose) and binding affinity (inhibition of receptorbinding of125I-insulin) on rat fat cells and the follo...

    Dr. J. Gliemann, S. Gammeltoft in Diabetologia (1974)

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