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Open AccessWhat can rodent models tell us about apathy and associated neuropsychiatric symptoms in Parkinson’s disease?
In addition to classical motor symptoms, Parkinson’s disease (PD) patients display incapacitating neuropsychiatric manifestations, such as apathy, anhedonia, depression and anxiety. These hitherto generally ne...
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Open AccessImplication of dopamine D3 receptor activation in the reversion of Parkinson’s disease-related motivational deficits
In addition to the classical motor symptoms, motivational and affective deficits are core impairments of Parkinson's disease (PD). We recently demonstrated, by lesional approaches in rats, that degeneration of...
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Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson’s disease
Parkinson’s disease (PD) involves the degeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) that is thought to cause the classical motor symptoms of this disease. However, motiv...
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Article
Open AccessImpact of sentinel node biopsy on long-term quality of life in breast cancer patients
The aim of this study was to assess long-term quality of life (QoL) over a period of 6 years in women with breast cancer (BC) who underwent sentinel lymph node biopsy (SLNB), axillary lymph node dissection (AL...
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Trisomie 12 en mosaïque diagnostiquée sur signes d’appel échographiques
La trisomie 12 en mosaïque est une mosaïque chromosomique rare, ce qui rend son diagnostic anténatal et sa prise en charge délicats. On retrouve dans la littérature 36 cas dépistés en période anténatale, six e...
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